Siz2 Prevents Ribosomal DNA Recombination by Modulating Levels of Tof2 in <named-content content-type="genus-species">Saccharomyces cerevisiae</named-content>

Siz2 Prevents Ribosomal DNA Recombination by Modulating Levels of Tof2 in <named-content content-type="genus-species">Saccharomyces cerevisiae</named-content>

ABSTRACT Ribosomal DNA (rDNA) recombination in budding yeast is regulated by multiple converging processes, including posttranslational modifications such as SUMOylation. In this study, we report that the absence of a SUMO E3 ligase, Siz2, results in increased unequal rDNA exchange. We show that Siz...

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Autores principales: Neethu Maria Abraham, Kathirvel Ramalingam, Saketh Murthy, Krishnaveni Mishra
Formato: article
Lenguaje:EN
Publicado: American Society for Microbiology 2019
Materias:
rDNA recombination
Siz2
Ulp2
Fob1
Tof2
SUMOylation
Microbiology
QR1-502
Acceso en línea:https://doaj.org/article/6942d82c98e94ec28ae18655179138f1
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