Evaluation of the progression of visual field damage in patients suffering from early manifest glaucoma

Andrea Perdicchi,1 Solmaz Abdolrahimzadeh,2 Alessandro Cutini,1 Angela Ciarnella,1 Gian Luca Scuderi1 1Ophthalmology Unit, Facoltà Medicina e Psicologia, Ospedale Sant’Andrea, 2Ophthalmology Unit, DAI Testa/Collo Policlinico Umberto I, Sapienza University of Rome, Rome,...

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Autores principales:	Perdicchi A, Abdolrahimzadeh S, Cutini A, Ciarnella A, Scuderi GL
Formato:	article
Lenguaje:	EN
Publicado:	Dove Medical Press 2016
Materias:	GLAUCOMA VISUAL FIELD PROGRESSION PERIMETRY. Ophthalmology RE1-994
Acceso en línea:	https://doaj.org/article/694a7700e01b4f24ab6df5071d360b61
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spelling	oai:doaj.org-article:694a7700e01b4f24ab6df5071d360b612021-12-02T06:45:15ZEvaluation of the progression of visual field damage in patients suffering from early manifest glaucoma1177-5483https://doaj.org/article/694a7700e01b4f24ab6df5071d360b612016-08-01T00:00:00Zhttps://www.dovepress.com/evaluation-of-the-progression-of-visual-field-damage-in-patients-suffe-peer-reviewed-article-OPTHhttps://doaj.org/toc/1177-5483Andrea Perdicchi,1 Solmaz Abdolrahimzadeh,2 Alessandro Cutini,1 Angela Ciarnella,1 Gian Luca Scuderi1 1Ophthalmology Unit, Facoltà Medicina e Psicologia, Ospedale Sant’Andrea, 2Ophthalmology Unit, DAI Testa/Collo Policlinico Umberto I, Sapienza University of Rome, Rome, Italy Background: This retrospective study aimed to determine how often a perimetric examination should be carried out in order to identify visual field (VF) changes in patients with relatively early manifestation glaucoma.Materials and methods: Patients included had a relatively recent manifestation of primary open-angle glaucoma. Patients with a minimum follow-up of 5 years and a minimum of seven VF tests were included. Statistical analysis was performed to verify the trend of variations in mean defect (MD) over time (PeriData). The results were subjected to a t-test for a comparative analysis of progression of VF changes over time. The annual rate of progression provided by PeriData considering all the VFs analyzed was compared with that obtained on half of the VF examinations during the same follow-up period. An analysis of the MD trend over time was also carried out in relationship to the number of VF tests done and by dividing the sample into a high-frequency group (more than eight VFs) and a low-frequency group (fewer than eight VFs) in the follow-up period.Results: A total of 96 eyes of 96 patients were included, and overall 846 VFs were examined. The paired t-test performed comparing the MD index of all the VFs against half of them did not show statistical significance (P=0.537). The high-frequency group comprised 39 eyes (average VF 11.05±1.91, average time interval 0.76 years) while the low-frequency group comprised 57 eyes (average VF 6.95±0.6, average time interval 1.21 years). The analysis of the MD trend in the high-frequency patients showed significance (P=0.017); the low-frequency group did not show statistical significance (P=0.08).Conclusion: The number of VFs in a determined time interval was not significant. However, a greater frequency of tests provides a predictive evaluation of the rate of progression of early manifestation open-angle glaucoma. Keywords: open-angle glaucoma, visual field, progression, ocular hypertensionPerdicchi AAbdolrahimzadeh SCutini ACiarnella AScuderi GLDove Medical PressarticleGLAUCOMAVISUAL FIELDPROGRESSIONPERIMETRY.OphthalmologyRE1-994ENClinical Ophthalmology, Vol Volume 10, Pp 1647-1651 (2016)
institution	DOAJ
collection	DOAJ
language	EN
topic	GLAUCOMA VISUAL FIELD PROGRESSION PERIMETRY. Ophthalmology RE1-994
spellingShingle	GLAUCOMA VISUAL FIELD PROGRESSION PERIMETRY. Ophthalmology RE1-994 Perdicchi A Abdolrahimzadeh S Cutini A Ciarnella A Scuderi GL Evaluation of the progression of visual field damage in patients suffering from early manifest glaucoma
description	Andrea Perdicchi,1 Solmaz Abdolrahimzadeh,2 Alessandro Cutini,1 Angela Ciarnella,1 Gian Luca Scuderi1 1Ophthalmology Unit, Facoltà Medicina e Psicologia, Ospedale Sant’Andrea, 2Ophthalmology Unit, DAI Testa/Collo Policlinico Umberto I, Sapienza University of Rome, Rome, Italy Background: This retrospective study aimed to determine how often a perimetric examination should be carried out in order to identify visual field (VF) changes in patients with relatively early manifestation glaucoma.Materials and methods: Patients included had a relatively recent manifestation of primary open-angle glaucoma. Patients with a minimum follow-up of 5 years and a minimum of seven VF tests were included. Statistical analysis was performed to verify the trend of variations in mean defect (MD) over time (PeriData). The results were subjected to a t-test for a comparative analysis of progression of VF changes over time. The annual rate of progression provided by PeriData considering all the VFs analyzed was compared with that obtained on half of the VF examinations during the same follow-up period. An analysis of the MD trend over time was also carried out in relationship to the number of VF tests done and by dividing the sample into a high-frequency group (more than eight VFs) and a low-frequency group (fewer than eight VFs) in the follow-up period.Results: A total of 96 eyes of 96 patients were included, and overall 846 VFs were examined. The paired t-test performed comparing the MD index of all the VFs against half of them did not show statistical significance (P=0.537). The high-frequency group comprised 39 eyes (average VF 11.05±1.91, average time interval 0.76 years) while the low-frequency group comprised 57 eyes (average VF 6.95±0.6, average time interval 1.21 years). The analysis of the MD trend in the high-frequency patients showed significance (P=0.017); the low-frequency group did not show statistical significance (P=0.08).Conclusion: The number of VFs in a determined time interval was not significant. However, a greater frequency of tests provides a predictive evaluation of the rate of progression of early manifestation open-angle glaucoma. Keywords: open-angle glaucoma, visual field, progression, ocular hypertension
format	article
author	Perdicchi A Abdolrahimzadeh S Cutini A Ciarnella A Scuderi GL
author_facet	Perdicchi A Abdolrahimzadeh S Cutini A Ciarnella A Scuderi GL
author_sort	Perdicchi A
title	Evaluation of the progression of visual field damage in patients suffering from early manifest glaucoma
title_short	Evaluation of the progression of visual field damage in patients suffering from early manifest glaucoma
title_full	Evaluation of the progression of visual field damage in patients suffering from early manifest glaucoma
title_fullStr	Evaluation of the progression of visual field damage in patients suffering from early manifest glaucoma
title_full_unstemmed	Evaluation of the progression of visual field damage in patients suffering from early manifest glaucoma
title_sort	evaluation of the progression of visual field damage in patients suffering from early manifest glaucoma
publisher	Dove Medical Press
publishDate	2016
url	https://doaj.org/article/694a7700e01b4f24ab6df5071d360b61
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_version_	1718399756834701312

Evaluation of the progression of visual field damage in patients suffering from early manifest glaucoma

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