Evaluation of Antihemagglutinin and Antineuraminidase Antibodies as Correlates of Protection in an Influenza A/H1N1 Virus Healthy Human Challenge Model

Evaluation of Antihemagglutinin and Antineuraminidase Antibodies as Correlates of Protection in an Influenza A/H1N1 Virus Healthy Human Challenge Model

ABSTRACT Despite long-term investment, influenza continues to be a significant worldwide problem. The cornerstone of protection remains vaccination, and approved vaccines seek to elicit a hemagglutination inhibition (HAI) titer of ≥1:40 as the primary correlate of protection. However, recent poor va...

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Autores principales: Matthew J. Memoli, Pamela A. Shaw, Alison Han, Lindsay Czajkowski, Susan Reed, Rani Athota, Tyler Bristol, Sarah Fargis, Kyle Risos, John H. Powers, Richard T. Davey, Jeffery K. Taubenberger
Formato: article
Lenguaje:EN
Publicado: American Society for Microbiology 2016
Materias:
Microbiology
QR1-502
Acceso en línea:https://doaj.org/article/694f641016cb4ea9addfbf7e2e2bbb3f
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