Predictors of major lower limb amputation in type 2 diabetic patients referred for hospital care with diabetic foot syndrome

Nawaf J Shatnawi,1 Nabil A Al-Zoubi,1 Hassan M Hawamdeh,2 Yousef S Khader,3 Khaled Garaibeh,4 Hussein A Heis1 1Department of Surgery, Jordan University of Science and Technology, Irbid, Jordan; 2Department of Basic Medical Science, Jordan University of Science and Technology, Irbid, Jordan; 3Departm...

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Autores principales:	Shatnawi NJ, Al-Zoubi NA, Hawamdeh HM, Khader YS, Gharaibeh K, Heis HA
Formato:	article
Lenguaje:	EN
Publicado:	Dove Medical Press 2018
Materias:	Diabetes Mellitus Amputations Diabetic Foot Syndrome gangrene. Specialties of internal medicine RC581-951
Acceso en línea:	https://doaj.org/article/69610fa5c2844d4fbeb02f81e87bd202
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spelling	oai:doaj.org-article:69610fa5c2844d4fbeb02f81e87bd2022021-12-02T06:57:58ZPredictors of major lower limb amputation in type 2 diabetic patients referred for hospital care with diabetic foot syndrome1178-7007https://doaj.org/article/69610fa5c2844d4fbeb02f81e87bd2022018-06-01T00:00:00Zhttps://www.dovepress.com/predictors-of-major-lower-limb-amputation-in-type-2-diabetic-patients--peer-reviewed-article-DMSOhttps://doaj.org/toc/1178-7007Nawaf J Shatnawi,1 Nabil A Al-Zoubi,1 Hassan M Hawamdeh,2 Yousef S Khader,3 Khaled Garaibeh,4 Hussein A Heis1 1Department of Surgery, Jordan University of Science and Technology, Irbid, Jordan; 2Department of Basic Medical Science, Jordan University of Science and Technology, Irbid, Jordan; 3Department of Community Medicine, Public Health and Family Medicine, Jordan University of Science and Technology, Irbid, Jordan; 4Department of Orthopedic Surgery, Jordan University of Science and Technology, Irbid, Jordan Purpose: This study was conducted to determine the risk factors of major lower extremity amputations in type 2 diabetic patients referred for hospital care with diabetic foot syndrome. Patients and methods: This retrospective study involved 225 type 2 diabetic patients referred for management of diabetic foot syndrome at King Abdullah University Hospital in the period between January 2014 and December 2015. A structured customized diabetic foot data collection form with diabetic foot characteristics chart was used for documentation of relevant information, which checks for age, sex, body mass index, smoking, duration of diabetes, diabetic control therapy, associated hypertension, cardiac diseases, stroke, chronic renal impairment, renal replacement therapy (hem-dialysis), and history of diabetes-related complication in both feet prior to the study period. The predictors for major lower limb amputations were compared between groups using chi-square test, and binary logistic regression was used to determine the factors associated with major amputation. Results: Twenty-seven limbs underwent major amputations with an overall rate of major amputation of 11.6%. The following predictors were found to be associated with the higher incidence of major lower limb amputations: duration of diabetes ≥15 years, HbA1c ≥8%, patients on insulin, with hypertension, cardiac diseases, chronic renal impairment, stroke, having gangrene, higher number of components, higher Wagner classification, and ischemia. However, the rate did not differ significantly between men and women. Conclusion: Presentation with gangrenous tissue and poor glycemic control are the important risks and significant predictive factors for type 2 diabetes-related major lower limb amputations. Keywords: diabetes mellitus, amputations, diabetic foot complication, gangreneShatnawi NJAl-Zoubi NAHawamdeh HMKhader YSGharaibeh KHeis HADove Medical PressarticleDiabetes MellitusAmputationsDiabetic Foot Syndromegangrene.Specialties of internal medicineRC581-951ENDiabetes, Metabolic Syndrome and Obesity: Targets and Therapy, Vol Volume 11, Pp 313-319 (2018)
institution	DOAJ
collection	DOAJ
language	EN
topic	Diabetes Mellitus Amputations Diabetic Foot Syndrome gangrene. Specialties of internal medicine RC581-951
spellingShingle	Diabetes Mellitus Amputations Diabetic Foot Syndrome gangrene. Specialties of internal medicine RC581-951 Shatnawi NJ Al-Zoubi NA Hawamdeh HM Khader YS Gharaibeh K Heis HA Predictors of major lower limb amputation in type 2 diabetic patients referred for hospital care with diabetic foot syndrome
description	Nawaf J Shatnawi,1 Nabil A Al-Zoubi,1 Hassan M Hawamdeh,2 Yousef S Khader,3 Khaled Garaibeh,4 Hussein A Heis1 1Department of Surgery, Jordan University of Science and Technology, Irbid, Jordan; 2Department of Basic Medical Science, Jordan University of Science and Technology, Irbid, Jordan; 3Department of Community Medicine, Public Health and Family Medicine, Jordan University of Science and Technology, Irbid, Jordan; 4Department of Orthopedic Surgery, Jordan University of Science and Technology, Irbid, Jordan Purpose: This study was conducted to determine the risk factors of major lower extremity amputations in type 2 diabetic patients referred for hospital care with diabetic foot syndrome. Patients and methods: This retrospective study involved 225 type 2 diabetic patients referred for management of diabetic foot syndrome at King Abdullah University Hospital in the period between January 2014 and December 2015. A structured customized diabetic foot data collection form with diabetic foot characteristics chart was used for documentation of relevant information, which checks for age, sex, body mass index, smoking, duration of diabetes, diabetic control therapy, associated hypertension, cardiac diseases, stroke, chronic renal impairment, renal replacement therapy (hem-dialysis), and history of diabetes-related complication in both feet prior to the study period. The predictors for major lower limb amputations were compared between groups using chi-square test, and binary logistic regression was used to determine the factors associated with major amputation. Results: Twenty-seven limbs underwent major amputations with an overall rate of major amputation of 11.6%. The following predictors were found to be associated with the higher incidence of major lower limb amputations: duration of diabetes ≥15 years, HbA1c ≥8%, patients on insulin, with hypertension, cardiac diseases, chronic renal impairment, stroke, having gangrene, higher number of components, higher Wagner classification, and ischemia. However, the rate did not differ significantly between men and women. Conclusion: Presentation with gangrenous tissue and poor glycemic control are the important risks and significant predictive factors for type 2 diabetes-related major lower limb amputations. Keywords: diabetes mellitus, amputations, diabetic foot complication, gangrene
format	article
author	Shatnawi NJ Al-Zoubi NA Hawamdeh HM Khader YS Gharaibeh K Heis HA
author_facet	Shatnawi NJ Al-Zoubi NA Hawamdeh HM Khader YS Gharaibeh K Heis HA
author_sort	Shatnawi NJ
title	Predictors of major lower limb amputation in type 2 diabetic patients referred for hospital care with diabetic foot syndrome
title_short	Predictors of major lower limb amputation in type 2 diabetic patients referred for hospital care with diabetic foot syndrome
title_full	Predictors of major lower limb amputation in type 2 diabetic patients referred for hospital care with diabetic foot syndrome
title_fullStr	Predictors of major lower limb amputation in type 2 diabetic patients referred for hospital care with diabetic foot syndrome
title_full_unstemmed	Predictors of major lower limb amputation in type 2 diabetic patients referred for hospital care with diabetic foot syndrome
title_sort	predictors of major lower limb amputation in type 2 diabetic patients referred for hospital care with diabetic foot syndrome
publisher	Dove Medical Press
publishDate	2018
url	https://doaj.org/article/69610fa5c2844d4fbeb02f81e87bd202
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Predictors of major lower limb amputation in type 2 diabetic patients referred for hospital care with diabetic foot syndrome

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