Pancreatic cancer prognosis is predicted by an ATAC-array technology for assessing chromatin accessibility

Pancreatic cancer prognosis is predicted by an ATAC-array technology for assessing chromatin accessibility

ATAC-seq allows for the investigation of chromatin accessibility, a feature which can have important implications for gene regulation. Here the authors present ATAC-array to assess accessibility in human tumours and based on this predict disease prognosis.

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Autores principales: S. Dhara, S. Chhangawala, H. Chintalapudi, G. Askan, V. Aveson, A. L. Massa, L. Zhang, D. Torres, A. P. Makohon-Moore, N. Lecomte, J. P. Melchor, J. Bermeo, A. Cardenas, S. Sinha, D. Glassman, R. Nicolle, R. Moffitt, K. H. Yu, S. Leppanen, S. Laderman, B. Curry, J. Gui, V. P. Balachandran, C. Iacobuzio-Donahue, R. Chandwani, C. S. Leslie, S. D. Leach
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2021
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Acceso en línea:https://doaj.org/article/6977d7f3af4b4cfabd67f3e6911c6b38
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spelling oai:doaj.org-article:6977d7f3af4b4cfabd67f3e6911c6b382021-12-02T15:00:50ZPancreatic cancer prognosis is predicted by an ATAC-array technology for assessing chromatin accessibility10.1038/s41467-021-23237-22041-1723https://doaj.org/article/6977d7f3af4b4cfabd67f3e6911c6b382021-05-01T00:00:00Zhttps://doi.org/10.1038/s41467-021-23237-2https://doaj.org/toc/2041-1723ATAC-seq allows for the investigation of chromatin accessibility, a feature which can have important implications for gene regulation. Here the authors present ATAC-array to assess accessibility in human tumours and based on this predict disease prognosis.S. DharaS. ChhangawalaH. ChintalapudiG. AskanV. AvesonA. L. MassaL. ZhangD. TorresA. P. Makohon-MooreN. LecomteJ. P. MelchorJ. BermeoA. CardenasS. SinhaD. GlassmanR. NicolleR. MoffittK. H. YuS. LeppanenS. LadermanB. CurryJ. GuiV. P. BalachandranC. Iacobuzio-DonahueR. ChandwaniC. S. LeslieS. D. LeachNature PortfolioarticleScienceQENNature Communications, Vol 12, Iss 1, Pp 1-9 (2021)
institution DOAJ
collection DOAJ
language EN
topic Science
Q
spellingShingle Science
Q
S. Dhara
S. Chhangawala
H. Chintalapudi
G. Askan
V. Aveson
A. L. Massa
L. Zhang
D. Torres
A. P. Makohon-Moore
N. Lecomte
J. P. Melchor
J. Bermeo
A. Cardenas
S. Sinha
D. Glassman
R. Nicolle
R. Moffitt
K. H. Yu
S. Leppanen
S. Laderman
B. Curry
J. Gui
V. P. Balachandran
C. Iacobuzio-Donahue
R. Chandwani
C. S. Leslie
S. D. Leach
Pancreatic cancer prognosis is predicted by an ATAC-array technology for assessing chromatin accessibility
description ATAC-seq allows for the investigation of chromatin accessibility, a feature which can have important implications for gene regulation. Here the authors present ATAC-array to assess accessibility in human tumours and based on this predict disease prognosis.
format article
author S. Dhara
S. Chhangawala
H. Chintalapudi
G. Askan
V. Aveson
A. L. Massa
L. Zhang
D. Torres
A. P. Makohon-Moore
N. Lecomte
J. P. Melchor
J. Bermeo
A. Cardenas
S. Sinha
D. Glassman
R. Nicolle
R. Moffitt
K. H. Yu
S. Leppanen
S. Laderman
B. Curry
J. Gui
V. P. Balachandran
C. Iacobuzio-Donahue
R. Chandwani
C. S. Leslie
S. D. Leach
author_facet S. Dhara
S. Chhangawala
H. Chintalapudi
G. Askan
V. Aveson
A. L. Massa
L. Zhang
D. Torres
A. P. Makohon-Moore
N. Lecomte
J. P. Melchor
J. Bermeo
A. Cardenas
S. Sinha
D. Glassman
R. Nicolle
R. Moffitt
K. H. Yu
S. Leppanen
S. Laderman
B. Curry
J. Gui
V. P. Balachandran
C. Iacobuzio-Donahue
R. Chandwani
C. S. Leslie
S. D. Leach
author_sort S. Dhara
title Pancreatic cancer prognosis is predicted by an ATAC-array technology for assessing chromatin accessibility
title_short Pancreatic cancer prognosis is predicted by an ATAC-array technology for assessing chromatin accessibility
title_full Pancreatic cancer prognosis is predicted by an ATAC-array technology for assessing chromatin accessibility
title_fullStr Pancreatic cancer prognosis is predicted by an ATAC-array technology for assessing chromatin accessibility
title_full_unstemmed Pancreatic cancer prognosis is predicted by an ATAC-array technology for assessing chromatin accessibility
title_sort pancreatic cancer prognosis is predicted by an atac-array technology for assessing chromatin accessibility
publisher Nature Portfolio
publishDate 2021
url https://doaj.org/article/6977d7f3af4b4cfabd67f3e6911c6b38
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