Marrying chemistry with biology by combining on-chip solution-based combinatorial synthesis and cellular screening
High-throughput cell-based screening of compound libraries is utilised in drug development; however, a lack of compatible methods limits direct synthesis and testing. Here, the authors present a diverse chip based synthesis system which can be combined with cell screening and demonstrate the applica...
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Auteurs principaux: | , , , , |
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Format: | article |
Langue: | EN |
Publié: |
Nature Portfolio
2019
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Accès en ligne: | https://doaj.org/article/6979685daa8a4f89bb0739d8f7eb3a4f |
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Résumé: | High-throughput cell-based screening of compound libraries is utilised in drug development; however, a lack of compatible methods limits direct synthesis and testing. Here, the authors present a diverse chip based synthesis system which can be combined with cell screening and demonstrate the application. |
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