Single-nucleus RNA-seq2 reveals functional crosstalk between liver zonation and ploidy

Single-nucleus RNA-seq2 reveals functional crosstalk between liver zonation and ploidy

Single-cell RNA-seq reveals the cellular heterogeneity in development and disease. Here the authors present a single-nucleus RNA-seq2 that allows deep characterization of nuclei isolated from frozen archived tissues, apply it for transcriptional profiling of individual hepatocytes, and determine a f...

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Autores principales: M. L. Richter, I. K. Deligiannis, K. Yin, A. Danese, E. Lleshi, P. Coupland, C. A. Vallejos, K. P. Matchett, N. C. Henderson, M. Colome-Tatche, C. P. Martinez-Jimenez
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2021
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Science
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Acceso en línea:https://doaj.org/article/697a3cd8916241ab8ea28bf7c44f29bd
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