Vesicoureteral Reflux and Renal Scarring in Infants

BACKGROUND AND OBJECTIVE: In spite of recent developments in treatment of urinary tract infection (UTI) in children, renal damage and scar can be associated with UTI and vesicoureteral reflux (VUR). The risk of renal damage is more in children with younger age, especially in children under one year....

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Autores principales: H Sorkhi, B Rajifar
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Lenguaje:EN
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Publicado: Babol University of Medical Sciences 2010
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Acceso en línea:https://doaj.org/article/698871971c2b4b8fa40f873300ba8544
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spelling oai:doaj.org-article:698871971c2b4b8fa40f873300ba85442021-11-10T09:00:22ZVesicoureteral Reflux and Renal Scarring in Infants1561-41072251-7170https://doaj.org/article/698871971c2b4b8fa40f873300ba85442010-06-01T00:00:00Zhttp://jbums.org/article-1-3494-en.htmlhttps://doaj.org/toc/1561-4107https://doaj.org/toc/2251-7170BACKGROUND AND OBJECTIVE: In spite of recent developments in treatment of urinary tract infection (UTI) in children, renal damage and scar can be associated with UTI and vesicoureteral reflux (VUR). The risk of renal damage is more in children with younger age, especially in children under one year. This study was done to evaluate the risk of renal scar presentation in infants with UIT and VUR. METHODS: This study was done on 71 children less than one year old with VUR and UIT that were referred to Amirkola Children Hospital (2007-2008). VUR was diagnosed by Voiding cystourethrography (VCUG) grade I-V and scar (grade I-IV) by DMSA (Dimercaptosuccinic acid) 4-6 months later. Then the results were surveyed.FINDINGS: Among 71 children, 49 (69%) patients were female.142 kidney units were evaluated and 114 (80.3%) units had VUR and the grades II (47.4%) was the most common grade of VUR. Among 142 renal units, 48 (38.8%) units had scar. The most common grade of scar was grade I (31 units, 64.6%). The most common grade of scar was seen in grade II of reflux (18 units, 37.5%).CONCLUSION: According to this study, more than one-third of children less than one year old with UIT and VUR had scar. So, more attention and good follow up are needed for UTI in this age group. Also the potential of scar formation before delivery must be mentioned.H Sorkhi,B RajifarBabol University of Medical Sciencesarticleinfantsurinary tract infection (uti)vesicoureteral reflux (vur)renal scarMedicineRMedicine (General)R5-920ENFAMajallah-i Dānishgāh-i ̒Ulūm-i Pizishkī-i Bābul, Vol 12, Iss 2, Pp 41-46 (2010)
institution DOAJ
collection DOAJ
language EN
FA
topic infants
urinary tract infection (uti)
vesicoureteral reflux (vur)
renal scar
Medicine
R
Medicine (General)
R5-920
spellingShingle infants
urinary tract infection (uti)
vesicoureteral reflux (vur)
renal scar
Medicine
R
Medicine (General)
R5-920
H Sorkhi,
B Rajifar
Vesicoureteral Reflux and Renal Scarring in Infants
description BACKGROUND AND OBJECTIVE: In spite of recent developments in treatment of urinary tract infection (UTI) in children, renal damage and scar can be associated with UTI and vesicoureteral reflux (VUR). The risk of renal damage is more in children with younger age, especially in children under one year. This study was done to evaluate the risk of renal scar presentation in infants with UIT and VUR. METHODS: This study was done on 71 children less than one year old with VUR and UIT that were referred to Amirkola Children Hospital (2007-2008). VUR was diagnosed by Voiding cystourethrography (VCUG) grade I-V and scar (grade I-IV) by DMSA (Dimercaptosuccinic acid) 4-6 months later. Then the results were surveyed.FINDINGS: Among 71 children, 49 (69%) patients were female.142 kidney units were evaluated and 114 (80.3%) units had VUR and the grades II (47.4%) was the most common grade of VUR. Among 142 renal units, 48 (38.8%) units had scar. The most common grade of scar was grade I (31 units, 64.6%). The most common grade of scar was seen in grade II of reflux (18 units, 37.5%).CONCLUSION: According to this study, more than one-third of children less than one year old with UIT and VUR had scar. So, more attention and good follow up are needed for UTI in this age group. Also the potential of scar formation before delivery must be mentioned.
format article
author H Sorkhi,
B Rajifar
author_facet H Sorkhi,
B Rajifar
author_sort H Sorkhi,
title Vesicoureteral Reflux and Renal Scarring in Infants
title_short Vesicoureteral Reflux and Renal Scarring in Infants
title_full Vesicoureteral Reflux and Renal Scarring in Infants
title_fullStr Vesicoureteral Reflux and Renal Scarring in Infants
title_full_unstemmed Vesicoureteral Reflux and Renal Scarring in Infants
title_sort vesicoureteral reflux and renal scarring in infants
publisher Babol University of Medical Sciences
publishDate 2010
url https://doaj.org/article/698871971c2b4b8fa40f873300ba8544
work_keys_str_mv AT hsorkhi vesicoureteralrefluxandrenalscarringininfants
AT brajifar vesicoureteralrefluxandrenalscarringininfants
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