Estimation of the thermocapillary force and its applications to precise droplet control on a microfluidic chip

Abstract Droplet control through the use of light-induced thermocapillary effects has recently garnered attention due to its non-intrusive and multifunctional nature. An important issue in droplet control is the estimation of the thermocapillary force. The purpose of the present study is to estimate...

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Autores principales:	By June Won, Wooyoung Lee, Simon Song
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2017
Materias:	Medicine R Science Q
Acceso en línea:	https://doaj.org/article/69889148240e4bdcb2e329a1df0baa69
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spelling	oai:doaj.org-article:69889148240e4bdcb2e329a1df0baa692021-12-02T15:05:26ZEstimation of the thermocapillary force and its applications to precise droplet control on a microfluidic chip10.1038/s41598-017-03028-w2045-2322https://doaj.org/article/69889148240e4bdcb2e329a1df0baa692017-06-01T00:00:00Zhttps://doi.org/10.1038/s41598-017-03028-whttps://doaj.org/toc/2045-2322Abstract Droplet control through the use of light-induced thermocapillary effects has recently garnered attention due to its non-intrusive and multifunctional nature. An important issue in droplet control is the estimation of the thermocapillary force. The purpose of the present study is to estimate the thermocapillary force and propose empirical equations between the force and simply measurable key parameters such as droplet diameter and power of heat source. In addition, we aim to shift the droplet trajectory and develop an on-demand droplet routing system based on the estimation of the thermocapillary force. We illuminated a continuous phase with a 532 nm laser beam to minimize possible damage or property changes to target molecules contained within droplets. A mixture of light-absorbing material and oleic acid was used for the continuous phase fluid, while deionized water (DI water) was used for the dispersed phase fluid. We proposed empirical equations to estimate the thermocapillary force, which was then applied to precise droplet shifting and routing. We found that the shifting distance was linearly proportional to the thermocapillary force, and that an on-demand droplet routing system resulted in a success rate greater than 95%.By June WonWooyoung LeeSimon SongNature PortfolioarticleMedicineRScienceQENScientific Reports, Vol 7, Iss 1, Pp 1-9 (2017)
institution	DOAJ
collection	DOAJ
language	EN
topic	Medicine R Science Q
spellingShingle	Medicine R Science Q By June Won Wooyoung Lee Simon Song Estimation of the thermocapillary force and its applications to precise droplet control on a microfluidic chip
description	Abstract Droplet control through the use of light-induced thermocapillary effects has recently garnered attention due to its non-intrusive and multifunctional nature. An important issue in droplet control is the estimation of the thermocapillary force. The purpose of the present study is to estimate the thermocapillary force and propose empirical equations between the force and simply measurable key parameters such as droplet diameter and power of heat source. In addition, we aim to shift the droplet trajectory and develop an on-demand droplet routing system based on the estimation of the thermocapillary force. We illuminated a continuous phase with a 532 nm laser beam to minimize possible damage or property changes to target molecules contained within droplets. A mixture of light-absorbing material and oleic acid was used for the continuous phase fluid, while deionized water (DI water) was used for the dispersed phase fluid. We proposed empirical equations to estimate the thermocapillary force, which was then applied to precise droplet shifting and routing. We found that the shifting distance was linearly proportional to the thermocapillary force, and that an on-demand droplet routing system resulted in a success rate greater than 95%.
format	article
author	By June Won Wooyoung Lee Simon Song
author_facet	By June Won Wooyoung Lee Simon Song
author_sort	By June Won
title	Estimation of the thermocapillary force and its applications to precise droplet control on a microfluidic chip
title_short	Estimation of the thermocapillary force and its applications to precise droplet control on a microfluidic chip
title_full	Estimation of the thermocapillary force and its applications to precise droplet control on a microfluidic chip
title_fullStr	Estimation of the thermocapillary force and its applications to precise droplet control on a microfluidic chip
title_full_unstemmed	Estimation of the thermocapillary force and its applications to precise droplet control on a microfluidic chip
title_sort	estimation of the thermocapillary force and its applications to precise droplet control on a microfluidic chip
publisher	Nature Portfolio
publishDate	2017
url	https://doaj.org/article/69889148240e4bdcb2e329a1df0baa69
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_version_	1718388835251912704

Estimation of the thermocapillary force and its applications to precise droplet control on a microfluidic chip

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