Gastroesophageal reflux GWAS identifies risk loci that also associate with subsequent severe esophageal diseases
Gastroesophageal reflux disease (GERD) is a major risk factor for Barret’s esophagus (BE) and esophageal adenocarcinoma (EA). Here, An et al. report 25 genetic loci for GERD, many of which associate with BE and EA or with other traits such as BMI.
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Nature Portfolio
2019
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oai:doaj.org-article:69989b38dc994e248ea97c1493de2f412021-12-02T15:35:15ZGastroesophageal reflux GWAS identifies risk loci that also associate with subsequent severe esophageal diseases10.1038/s41467-019-11968-22041-1723https://doaj.org/article/69989b38dc994e248ea97c1493de2f412019-09-01T00:00:00Zhttps://doi.org/10.1038/s41467-019-11968-2https://doaj.org/toc/2041-1723Gastroesophageal reflux disease (GERD) is a major risk factor for Barret’s esophagus (BE) and esophageal adenocarcinoma (EA). Here, An et al. report 25 genetic loci for GERD, many of which associate with BE and EA or with other traits such as BMI.Jiyuan AnPuya GharahkhaniMatthew H. LawJue-Sheng OngXikun HanCatherine M. OlsenRachel E. NealeJohn LaiTom L. VaughanInes GockelRené ThiemeAnne C. BöhmerJanusz JankowskiRebecca C. FitzgeraldJohannes SchumacherClaire PallesBEACON23andMe Research TeamDavid C. WhitemanStuart MacGregorNature PortfolioarticleScienceQENNature Communications, Vol 10, Iss 1, Pp 1-10 (2019) |
| institution |
DOAJ |
| collection |
DOAJ |
| language |
EN |
| topic |
Science Q |
| spellingShingle |
Science Q Jiyuan An Puya Gharahkhani Matthew H. Law Jue-Sheng Ong Xikun Han Catherine M. Olsen Rachel E. Neale John Lai Tom L. Vaughan Ines Gockel René Thieme Anne C. Böhmer Janusz Jankowski Rebecca C. Fitzgerald Johannes Schumacher Claire Palles BEACON 23andMe Research Team David C. Whiteman Stuart MacGregor Gastroesophageal reflux GWAS identifies risk loci that also associate with subsequent severe esophageal diseases |
| description |
Gastroesophageal reflux disease (GERD) is a major risk factor for Barret’s esophagus (BE) and esophageal adenocarcinoma (EA). Here, An et al. report 25 genetic loci for GERD, many of which associate with BE and EA or with other traits such as BMI. |
| format |
article |
| author |
Jiyuan An Puya Gharahkhani Matthew H. Law Jue-Sheng Ong Xikun Han Catherine M. Olsen Rachel E. Neale John Lai Tom L. Vaughan Ines Gockel René Thieme Anne C. Böhmer Janusz Jankowski Rebecca C. Fitzgerald Johannes Schumacher Claire Palles BEACON 23andMe Research Team David C. Whiteman Stuart MacGregor |
| author_facet |
Jiyuan An Puya Gharahkhani Matthew H. Law Jue-Sheng Ong Xikun Han Catherine M. Olsen Rachel E. Neale John Lai Tom L. Vaughan Ines Gockel René Thieme Anne C. Böhmer Janusz Jankowski Rebecca C. Fitzgerald Johannes Schumacher Claire Palles BEACON 23andMe Research Team David C. Whiteman Stuart MacGregor |
| author_sort |
Jiyuan An |
| title |
Gastroesophageal reflux GWAS identifies risk loci that also associate with subsequent severe esophageal diseases |
| title_short |
Gastroesophageal reflux GWAS identifies risk loci that also associate with subsequent severe esophageal diseases |
| title_full |
Gastroesophageal reflux GWAS identifies risk loci that also associate with subsequent severe esophageal diseases |
| title_fullStr |
Gastroesophageal reflux GWAS identifies risk loci that also associate with subsequent severe esophageal diseases |
| title_full_unstemmed |
Gastroesophageal reflux GWAS identifies risk loci that also associate with subsequent severe esophageal diseases |
| title_sort |
gastroesophageal reflux gwas identifies risk loci that also associate with subsequent severe esophageal diseases |
| publisher |
Nature Portfolio |
| publishDate |
2019 |
| url |
https://doaj.org/article/69989b38dc994e248ea97c1493de2f41 |
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