Clinically applicable GABA receptor positive allosteric modulators promote ß-cell replication
A key goal of diabetes research is to develop treatments to safely promote human ß-cell replication. It has recently become appreciated that activation of γ-aminobutyric acid receptors (GABA-Rs) on ß-cells can promote their survival and replication. A number of positive allosteric modulators (PAMs)...
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Autores principales: | Jide Tian, Hoa Dang, Blake Middleton, Daniel L. Kaufman |
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Formato: | article |
Lenguaje: | EN |
Publicado: |
Nature Portfolio
2017
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Materias: | |
Acceso en línea: | https://doaj.org/article/699c7694478c4951878f8b73c833f82b |
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