Does skin permeation kinetics influence efficacy of topical dermal drug delivery system?: Assessment, prediction, utilization, and integration of chitosan biomacromolecule for augmenting topical dermal drug delivery in skin

Does skin permeation kinetics influence efficacy of topical dermal drug delivery system?: Assessment, prediction, utilization, and integration of chitosan biomacromolecule for augmenting topical dermal drug delivery in skin

Skin permeation is an integral part of penetration of topical therapeutics. Zero order in addition to Higuchi permeation kinetic is usually preferred in topical drug delivery cargo. Penetration of therapeutic entities through epidermal barrier is a major challenge for scientific fraternity. Furtherm...

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Bibliographic Details
Main Authors: Akshaya Iyer, Vaskuri G. S. Sainaga Jyothi, Aashruti Agrawal, Dharmendra Kumar Khatri, Saurabh Srivastava, Shashi Bala Singh, Jitender Madan
Format: article
Language:EN
Published: Wolters Kluwer Medknow Publications 2021
Subjects:
artificial neural network
chitosan biomacromolecule
in silico docking
permeation
skin
topical delivery
Therapeutics. Pharmacology
RM1-950
Pharmacy and materia medica
RS1-441
Online Access:https://doaj.org/article/69a36a08b0d84579ac6dc2dba08136aa
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https://doaj.org/article/69a36a08b0d84579ac6dc2dba08136aa

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