Parkin promotes degradation of the mitochondrial pro-apoptotic ARTS protein.

Parkin promotes degradation of the mitochondrial pro-apoptotic ARTS protein.

Parkinson's disease (PD) is associated with excessive cell death causing selective loss of dopaminergic neurons. Dysfunction of the Ubiquitin Proteasome System (UPS) is associated with the pathophysiology of PD. Mutations in Parkin which impair its E3-ligase activity play a major role in the pa...

Descripción completa

Guardado en:
Detalles Bibliográficos
Autores principales: Stav Kemeny, Dikla Dery, Yelena Loboda, Marshall Rovner, Tali Lev, Dotan Zuri, John P M Finberg, Sarit Larisch
Formato: article
Lenguaje:EN
Publicado: Public Library of Science (PLoS) 2012
Materias:
Medicine
R
Science
Q
Acceso en línea:https://doaj.org/article/69ad29b6430a4995b84f2c17c98c66f8
Etiquetas: Agregar Etiqueta
Sin Etiquetas, Sea el primero en etiquetar este registro!

Ejemplares similares

Ejemplares similares