Nocturnal Blood Pressure Fluctuations in Patients with Rapid Eye Movement-Related Obstructive Sleep Apnea

Rapid eye movement-related obstructive sleep apnea (REM-related OSA) is a polysomnographic phenotype. Nocturnal blood pressure (BP) fluctuations remain unclear in patients with REM-related OSA. We studied 27 patients with REM-related OSA, categorized as having REM-apnea-hypopnea index (REM-AHI) ≥ 5/...

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Autores principales:	Hajime Kumagai, Hiroyuki Sawatari, Tetsuro Hoshino, Noriyuki Konishi, Yuka Kiyohara, Kengo Kawaguchi, Hiroko Tsuda, Yoko Haseda, Ryujiro Sasanabe, Toshiaki Shiomi
Formato:	article
Lenguaje:	EN
Publicado:	MDPI AG 2021
Materias:	rapid eye movement-related obstructive sleep apnea pulse transit time non-dipping pattern systolic blood pressure variability Medicine R
Acceso en línea:	https://doaj.org/article/69afe6423be446b0bda576152492d98f
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spelling	oai:doaj.org-article:69afe6423be446b0bda576152492d98f2021-11-11T17:39:08ZNocturnal Blood Pressure Fluctuations in Patients with Rapid Eye Movement-Related Obstructive Sleep Apnea10.3390/jcm102150232077-0383https://doaj.org/article/69afe6423be446b0bda576152492d98f2021-10-01T00:00:00Zhttps://www.mdpi.com/2077-0383/10/21/5023https://doaj.org/toc/2077-0383Rapid eye movement-related obstructive sleep apnea (REM-related OSA) is a polysomnographic phenotype. Nocturnal blood pressure (BP) fluctuations remain unclear in patients with REM-related OSA. We studied 27 patients with REM-related OSA, categorized as having REM-apnea-hypopnea index (REM-AHI) ≥ 5/h, REM-AHI/non-REM-AHI ≥ 2, and non-REM-AHI < 15/h. Beat-to-beat systolic BP (SBP) variability and nocturnal SBP fluctuation patterns using pulse transit time (PTT) were investigated. The maximum increase and average nocturnal SBP were significantly higher in males than in females (<i>p</i> = 0.003 and <i>p</i> = 0.008, respectively). The rate of non-dipping patterns in nocturnal SBP fluctuations was 63% in all patients (males, 70%; females, 50%). Epworth Sleepiness Scale (ESS) and Self-rating Depression Scale (SDS) scores in females were higher than those in males (8.4 ± 6.1 vs. 13.4 ± 5.4 points, <i>p</i> = 0.04; 43.8 ± 7.9 vs. 52 ± 11.6 points, <i>p</i> = 0.04, respectively). A high proportion of patients with REM-related OSA had a non-dipping pattern. Using PPT, we observed that in patients with REM-related OSA, SBP variability was greater in males. Despite clinical symptoms being slightly more severe in females, nocturnal SBP fluctuations should be considered in male patients with REM-related OSA.Hajime KumagaiHiroyuki SawatariTetsuro HoshinoNoriyuki KonishiYuka KiyoharaKengo KawaguchiHiroko TsudaYoko HasedaRyujiro SasanabeToshiaki ShiomiMDPI AGarticlerapid eye movement-related obstructive sleep apneapulse transit timenon-dipping patternsystolic blood pressure variabilityMedicineRENJournal of Clinical Medicine, Vol 10, Iss 5023, p 5023 (2021)
institution	DOAJ
collection	DOAJ
language	EN
topic	rapid eye movement-related obstructive sleep apnea pulse transit time non-dipping pattern systolic blood pressure variability Medicine R
spellingShingle	rapid eye movement-related obstructive sleep apnea pulse transit time non-dipping pattern systolic blood pressure variability Medicine R Hajime Kumagai Hiroyuki Sawatari Tetsuro Hoshino Noriyuki Konishi Yuka Kiyohara Kengo Kawaguchi Hiroko Tsuda Yoko Haseda Ryujiro Sasanabe Toshiaki Shiomi Nocturnal Blood Pressure Fluctuations in Patients with Rapid Eye Movement-Related Obstructive Sleep Apnea
description	Rapid eye movement-related obstructive sleep apnea (REM-related OSA) is a polysomnographic phenotype. Nocturnal blood pressure (BP) fluctuations remain unclear in patients with REM-related OSA. We studied 27 patients with REM-related OSA, categorized as having REM-apnea-hypopnea index (REM-AHI) ≥ 5/h, REM-AHI/non-REM-AHI ≥ 2, and non-REM-AHI < 15/h. Beat-to-beat systolic BP (SBP) variability and nocturnal SBP fluctuation patterns using pulse transit time (PTT) were investigated. The maximum increase and average nocturnal SBP were significantly higher in males than in females (<i>p</i> = 0.003 and <i>p</i> = 0.008, respectively). The rate of non-dipping patterns in nocturnal SBP fluctuations was 63% in all patients (males, 70%; females, 50%). Epworth Sleepiness Scale (ESS) and Self-rating Depression Scale (SDS) scores in females were higher than those in males (8.4 ± 6.1 vs. 13.4 ± 5.4 points, <i>p</i> = 0.04; 43.8 ± 7.9 vs. 52 ± 11.6 points, <i>p</i> = 0.04, respectively). A high proportion of patients with REM-related OSA had a non-dipping pattern. Using PPT, we observed that in patients with REM-related OSA, SBP variability was greater in males. Despite clinical symptoms being slightly more severe in females, nocturnal SBP fluctuations should be considered in male patients with REM-related OSA.
format	article
author	Hajime Kumagai Hiroyuki Sawatari Tetsuro Hoshino Noriyuki Konishi Yuka Kiyohara Kengo Kawaguchi Hiroko Tsuda Yoko Haseda Ryujiro Sasanabe Toshiaki Shiomi
author_facet	Hajime Kumagai Hiroyuki Sawatari Tetsuro Hoshino Noriyuki Konishi Yuka Kiyohara Kengo Kawaguchi Hiroko Tsuda Yoko Haseda Ryujiro Sasanabe Toshiaki Shiomi
author_sort	Hajime Kumagai
title	Nocturnal Blood Pressure Fluctuations in Patients with Rapid Eye Movement-Related Obstructive Sleep Apnea
title_short	Nocturnal Blood Pressure Fluctuations in Patients with Rapid Eye Movement-Related Obstructive Sleep Apnea
title_full	Nocturnal Blood Pressure Fluctuations in Patients with Rapid Eye Movement-Related Obstructive Sleep Apnea
title_fullStr	Nocturnal Blood Pressure Fluctuations in Patients with Rapid Eye Movement-Related Obstructive Sleep Apnea
title_full_unstemmed	Nocturnal Blood Pressure Fluctuations in Patients with Rapid Eye Movement-Related Obstructive Sleep Apnea
title_sort	nocturnal blood pressure fluctuations in patients with rapid eye movement-related obstructive sleep apnea
publisher	MDPI AG
publishDate	2021
url	https://doaj.org/article/69afe6423be446b0bda576152492d98f
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Nocturnal Blood Pressure Fluctuations in Patients with Rapid Eye Movement-Related Obstructive Sleep Apnea

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