Role of GATA binding protein 4 (GATA4) in the regulation of tooth development via GNAI3

Role of GATA binding protein 4 (GATA4) in the regulation of tooth development via GNAI3

Abstract Transcription factor GATA4 regulates cardiac and osteoblast differentiation. However, its role in tooth development is not clear. Therefore, we generated Wnt1-Cre;GATA4 fl/fl mice, with conditional inactivation of the GATA4 gene in the dental papilla mesenchymal cells. Phenotypic analysis s...

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Autores principales: Shuyu Guo, Yuxin Zhang, Tingting Zhou, Dongyue Wang, Yajuan Weng, Lin Wang, Junqing Ma
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2017
Materias:
Medicine
R
Science
Q
Acceso en línea:https://doaj.org/article/69b5792839b44590a9b8dbb15cae6819
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