Is prolonged febrile syndrome associated with reactive thrombocytosis a possible association in the diagnosis of Takayasu’s arteritis? A case report

Takayasu’s arteritis is a rare, systemic, inflammatory vasculitis of large blood vessels with an unknown aetiology that more frequently affects women of childbearing age with progression to stenosis, fibrosis or thrombogenesis. Clinical manifestations are associated either with inflammation of the v...

Descripción completa

Guardado en:
Detalles Bibliográficos
Autores principales: Victoria Birlutiu, Rares-Mircea Birlutiu, Mariana Sandu, Emmanuel Mihali-Oniga
Formato: article
Lenguaje:EN
Publicado: SAGE Publishing 2021
Materias:
Acceso en línea:https://doaj.org/article/69b82fb996774e40bb1a95964d63b9b6
Etiquetas: Agregar Etiqueta
Sin Etiquetas, Sea el primero en etiquetar este registro!
id oai:doaj.org-article:69b82fb996774e40bb1a95964d63b9b6
record_format dspace
spelling oai:doaj.org-article:69b82fb996774e40bb1a95964d63b9b62021-11-10T01:03:20ZIs prolonged febrile syndrome associated with reactive thrombocytosis a possible association in the diagnosis of Takayasu’s arteritis? A case report1473-230010.1177/03000605211055388https://doaj.org/article/69b82fb996774e40bb1a95964d63b9b62021-11-01T00:00:00Zhttps://doi.org/10.1177/03000605211055388https://doaj.org/toc/1473-2300Takayasu’s arteritis is a rare, systemic, inflammatory vasculitis of large blood vessels with an unknown aetiology that more frequently affects women of childbearing age with progression to stenosis, fibrosis or thrombogenesis. Clinical manifestations are associated either with inflammation of the vascular wall (including fever, myalgia, arthralgia, weight loss) or the development of aneurysms and extensive vascular lesions, which creates challenges for a differential diagnosis. This current report presents the case of a female Caucasian patient, aged 23 years, that presented herself repetitively at the hospital reporting symptoms including fever, productive cough, myalgia associated with physical effort, arthralgia, inconstant headache, weight loss and altered general condition. The patient was diagnosed with Takayasu’s arteritis in the context of a prolonged febrile syndrome associated with reactive thrombocytosis. This association results in the need to exclude multiple differential diagnoses. Nonspecific management was initiated, which included antibiotic treatment, antifungal medication, anticoagulants, steroidal anti-inflammatory drugs and correction of anaemia. The patient slowly improved. Takayasu’s arteritis in the inflammatory phase associated with a prolonged febrile syndrome and reactive thrombocytosis is a rare diagnosis of exclusion of a multitude of inflammatory diseases of large blood vessels, infectious diseases and neurofibromatosis, which requires multiple investigations for an accurate diagnosis and management.Victoria BirlutiuRares-Mircea BirlutiuMariana SanduEmmanuel Mihali-OnigaSAGE PublishingarticleMedicine (General)R5-920ENJournal of International Medical Research, Vol 49 (2021)
institution DOAJ
collection DOAJ
language EN
topic Medicine (General)
R5-920
spellingShingle Medicine (General)
R5-920
Victoria Birlutiu
Rares-Mircea Birlutiu
Mariana Sandu
Emmanuel Mihali-Oniga
Is prolonged febrile syndrome associated with reactive thrombocytosis a possible association in the diagnosis of Takayasu’s arteritis? A case report
description Takayasu’s arteritis is a rare, systemic, inflammatory vasculitis of large blood vessels with an unknown aetiology that more frequently affects women of childbearing age with progression to stenosis, fibrosis or thrombogenesis. Clinical manifestations are associated either with inflammation of the vascular wall (including fever, myalgia, arthralgia, weight loss) or the development of aneurysms and extensive vascular lesions, which creates challenges for a differential diagnosis. This current report presents the case of a female Caucasian patient, aged 23 years, that presented herself repetitively at the hospital reporting symptoms including fever, productive cough, myalgia associated with physical effort, arthralgia, inconstant headache, weight loss and altered general condition. The patient was diagnosed with Takayasu’s arteritis in the context of a prolonged febrile syndrome associated with reactive thrombocytosis. This association results in the need to exclude multiple differential diagnoses. Nonspecific management was initiated, which included antibiotic treatment, antifungal medication, anticoagulants, steroidal anti-inflammatory drugs and correction of anaemia. The patient slowly improved. Takayasu’s arteritis in the inflammatory phase associated with a prolonged febrile syndrome and reactive thrombocytosis is a rare diagnosis of exclusion of a multitude of inflammatory diseases of large blood vessels, infectious diseases and neurofibromatosis, which requires multiple investigations for an accurate diagnosis and management.
format article
author Victoria Birlutiu
Rares-Mircea Birlutiu
Mariana Sandu
Emmanuel Mihali-Oniga
author_facet Victoria Birlutiu
Rares-Mircea Birlutiu
Mariana Sandu
Emmanuel Mihali-Oniga
author_sort Victoria Birlutiu
title Is prolonged febrile syndrome associated with reactive thrombocytosis a possible association in the diagnosis of Takayasu’s arteritis? A case report
title_short Is prolonged febrile syndrome associated with reactive thrombocytosis a possible association in the diagnosis of Takayasu’s arteritis? A case report
title_full Is prolonged febrile syndrome associated with reactive thrombocytosis a possible association in the diagnosis of Takayasu’s arteritis? A case report
title_fullStr Is prolonged febrile syndrome associated with reactive thrombocytosis a possible association in the diagnosis of Takayasu’s arteritis? A case report
title_full_unstemmed Is prolonged febrile syndrome associated with reactive thrombocytosis a possible association in the diagnosis of Takayasu’s arteritis? A case report
title_sort is prolonged febrile syndrome associated with reactive thrombocytosis a possible association in the diagnosis of takayasu’s arteritis? a case report
publisher SAGE Publishing
publishDate 2021
url https://doaj.org/article/69b82fb996774e40bb1a95964d63b9b6
work_keys_str_mv AT victoriabirlutiu isprolongedfebrilesyndromeassociatedwithreactivethrombocytosisapossibleassociationinthediagnosisoftakayasusarteritisacasereport
AT raresmirceabirlutiu isprolongedfebrilesyndromeassociatedwithreactivethrombocytosisapossibleassociationinthediagnosisoftakayasusarteritisacasereport
AT marianasandu isprolongedfebrilesyndromeassociatedwithreactivethrombocytosisapossibleassociationinthediagnosisoftakayasusarteritisacasereport
AT emmanuelmihalioniga isprolongedfebrilesyndromeassociatedwithreactivethrombocytosisapossibleassociationinthediagnosisoftakayasusarteritisacasereport
_version_ 1718440751170322432