Inhibition of lncRNA H19/miR-370-3p pathway mitigates neuronal apoptosis in an in vitro model of spinal cord injury (SCI)

Spinal cord injury (SCI) is the most serious complication of spinal injury, often leading to severe dysfunction of the limbs below the injured segment. Conventional therapy approaches are becoming less and less effective, and gene therapy is a new research direction by now.

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Autores principales: Li Xin, Qian Yan, Tang Kaihua, Li Yang, Tao Rui, Gong Chunyan, Huang Li, Zou Kaiwen, Liu Lindong
Formato: article
Lenguaje:EN
Publicado: De Gruyter 2021
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Acceso en línea:https://doaj.org/article/69d369535764415596014994607767de
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spelling oai:doaj.org-article:69d369535764415596014994607767de2021-12-05T14:11:05ZInhibition of lncRNA H19/miR-370-3p pathway mitigates neuronal apoptosis in an in vitro model of spinal cord injury (SCI)2081-693610.1515/tnsci-2021-0013https://doaj.org/article/69d369535764415596014994607767de2021-03-01T00:00:00Zhttps://doi.org/10.1515/tnsci-2021-0013https://doaj.org/toc/2081-6936Spinal cord injury (SCI) is the most serious complication of spinal injury, often leading to severe dysfunction of the limbs below the injured segment. Conventional therapy approaches are becoming less and less effective, and gene therapy is a new research direction by now.Li XinQian YanTang KaihuaLi YangTao RuiGong ChunyanHuang LiZou KaiwenLiu LindongDe Gruyterarticlescilncrna h19mir-370-3pnf-κb pathwayNeurosciences. Biological psychiatry. NeuropsychiatryRC321-571ENTranslational Neuroscience, Vol 12, Iss 1, Pp 103-113 (2021)
institution DOAJ
collection DOAJ
language EN
topic sci
lncrna h19
mir-370-3p
nf-κb pathway
Neurosciences. Biological psychiatry. Neuropsychiatry
RC321-571
spellingShingle sci
lncrna h19
mir-370-3p
nf-κb pathway
Neurosciences. Biological psychiatry. Neuropsychiatry
RC321-571
Li Xin
Qian Yan
Tang Kaihua
Li Yang
Tao Rui
Gong Chunyan
Huang Li
Zou Kaiwen
Liu Lindong
Inhibition of lncRNA H19/miR-370-3p pathway mitigates neuronal apoptosis in an in vitro model of spinal cord injury (SCI)
description Spinal cord injury (SCI) is the most serious complication of spinal injury, often leading to severe dysfunction of the limbs below the injured segment. Conventional therapy approaches are becoming less and less effective, and gene therapy is a new research direction by now.
format article
author Li Xin
Qian Yan
Tang Kaihua
Li Yang
Tao Rui
Gong Chunyan
Huang Li
Zou Kaiwen
Liu Lindong
author_facet Li Xin
Qian Yan
Tang Kaihua
Li Yang
Tao Rui
Gong Chunyan
Huang Li
Zou Kaiwen
Liu Lindong
author_sort Li Xin
title Inhibition of lncRNA H19/miR-370-3p pathway mitigates neuronal apoptosis in an in vitro model of spinal cord injury (SCI)
title_short Inhibition of lncRNA H19/miR-370-3p pathway mitigates neuronal apoptosis in an in vitro model of spinal cord injury (SCI)
title_full Inhibition of lncRNA H19/miR-370-3p pathway mitigates neuronal apoptosis in an in vitro model of spinal cord injury (SCI)
title_fullStr Inhibition of lncRNA H19/miR-370-3p pathway mitigates neuronal apoptosis in an in vitro model of spinal cord injury (SCI)
title_full_unstemmed Inhibition of lncRNA H19/miR-370-3p pathway mitigates neuronal apoptosis in an in vitro model of spinal cord injury (SCI)
title_sort inhibition of lncrna h19/mir-370-3p pathway mitigates neuronal apoptosis in an in vitro model of spinal cord injury (sci)
publisher De Gruyter
publishDate 2021
url https://doaj.org/article/69d369535764415596014994607767de
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AT qianyan inhibitionoflncrnah19mir3703ppathwaymitigatesneuronalapoptosisinaninvitromodelofspinalcordinjurysci
AT tangkaihua inhibitionoflncrnah19mir3703ppathwaymitigatesneuronalapoptosisinaninvitromodelofspinalcordinjurysci
AT liyang inhibitionoflncrnah19mir3703ppathwaymitigatesneuronalapoptosisinaninvitromodelofspinalcordinjurysci
AT taorui inhibitionoflncrnah19mir3703ppathwaymitigatesneuronalapoptosisinaninvitromodelofspinalcordinjurysci
AT gongchunyan inhibitionoflncrnah19mir3703ppathwaymitigatesneuronalapoptosisinaninvitromodelofspinalcordinjurysci
AT huangli inhibitionoflncrnah19mir3703ppathwaymitigatesneuronalapoptosisinaninvitromodelofspinalcordinjurysci
AT zoukaiwen inhibitionoflncrnah19mir3703ppathwaymitigatesneuronalapoptosisinaninvitromodelofspinalcordinjurysci
AT liulindong inhibitionoflncrnah19mir3703ppathwaymitigatesneuronalapoptosisinaninvitromodelofspinalcordinjurysci
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