THE INFLUENCE OF COLLOID SILVER NANO-PARTICLES UPON IMMUNOBIOLOGIC PROPERTIES OF PLAGUE MICROBE CAPSULAR ANTIGEN
This study shows that Yersinia pestis capsular antigen F1 conjugated to the CS nano-particles demonstrates apparent immunogenic effects. When injected to the test animals it was able to stimulate the production of specific antibodies under smaller antigenic load, it caused activation of the genetic...
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Scientific Сentre for Family Health and Human Reproduction Problems
2012
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oai:doaj.org-article:69d655df6fb54eb39a473438897f04332021-11-23T06:14:24ZTHE INFLUENCE OF COLLOID SILVER NANO-PARTICLES UPON IMMUNOBIOLOGIC PROPERTIES OF PLAGUE MICROBE CAPSULAR ANTIGEN2541-94202587-9596https://doaj.org/article/69d655df6fb54eb39a473438897f04332012-09-01T00:00:00Zhttps://www.actabiomedica.ru/jour/article/view/1134https://doaj.org/toc/2541-9420https://doaj.org/toc/2587-9596This study shows that Yersinia pestis capsular antigen F1 conjugated to the CS nano-particles demonstrates apparent immunogenic effects. When injected to the test animals it was able to stimulate the production of specific antibodies under smaller antigenic load, it caused activation of the genetic apparatus in the immune system cells, and it stimulated hyperplastic processes in the lymphoid organs. Solutions of CS plus antigens appeared to be stable and caused neither general nor local responses in the test animals; they were easy to make use of, thus demonstrating their potentialities to be exploited as adjuvants in immunologic practices.M. N. KireyevN. P. GoosevaT. A. PoluninaA. L. KravtsovS. A. BugorkovaN. A. SharapovaT. M. TaranenkoScientific Сentre for Family Health and Human Reproduction Problemsarticleyersinia pestis capsular antigen f1immunobiological propertiesadjuvantScienceQRUActa Biomedica Scientifica, Vol 0, Iss 5(1), Pp 228-230 (2012) |
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| topic |
yersinia pestis capsular antigen f1 immunobiological properties adjuvant Science Q |
| spellingShingle |
yersinia pestis capsular antigen f1 immunobiological properties adjuvant Science Q M. N. Kireyev N. P. Gooseva T. A. Polunina A. L. Kravtsov S. A. Bugorkova N. A. Sharapova T. M. Taranenko THE INFLUENCE OF COLLOID SILVER NANO-PARTICLES UPON IMMUNOBIOLOGIC PROPERTIES OF PLAGUE MICROBE CAPSULAR ANTIGEN |
| description |
This study shows that Yersinia pestis capsular antigen F1 conjugated to the CS nano-particles demonstrates apparent immunogenic effects. When injected to the test animals it was able to stimulate the production of specific antibodies under smaller antigenic load, it caused activation of the genetic apparatus in the immune system cells, and it stimulated hyperplastic processes in the lymphoid organs. Solutions of CS plus antigens appeared to be stable and caused neither general nor local responses in the test animals; they were easy to make use of, thus demonstrating their potentialities to be exploited as adjuvants in immunologic practices. |
| format |
article |
| author |
M. N. Kireyev N. P. Gooseva T. A. Polunina A. L. Kravtsov S. A. Bugorkova N. A. Sharapova T. M. Taranenko |
| author_facet |
M. N. Kireyev N. P. Gooseva T. A. Polunina A. L. Kravtsov S. A. Bugorkova N. A. Sharapova T. M. Taranenko |
| author_sort |
M. N. Kireyev |
| title |
THE INFLUENCE OF COLLOID SILVER NANO-PARTICLES UPON IMMUNOBIOLOGIC PROPERTIES OF PLAGUE MICROBE CAPSULAR ANTIGEN |
| title_short |
THE INFLUENCE OF COLLOID SILVER NANO-PARTICLES UPON IMMUNOBIOLOGIC PROPERTIES OF PLAGUE MICROBE CAPSULAR ANTIGEN |
| title_full |
THE INFLUENCE OF COLLOID SILVER NANO-PARTICLES UPON IMMUNOBIOLOGIC PROPERTIES OF PLAGUE MICROBE CAPSULAR ANTIGEN |
| title_fullStr |
THE INFLUENCE OF COLLOID SILVER NANO-PARTICLES UPON IMMUNOBIOLOGIC PROPERTIES OF PLAGUE MICROBE CAPSULAR ANTIGEN |
| title_full_unstemmed |
THE INFLUENCE OF COLLOID SILVER NANO-PARTICLES UPON IMMUNOBIOLOGIC PROPERTIES OF PLAGUE MICROBE CAPSULAR ANTIGEN |
| title_sort |
influence of colloid silver nano-particles upon immunobiologic properties of plague microbe capsular antigen |
| publisher |
Scientific Сentre for Family Health and Human Reproduction Problems |
| publishDate |
2012 |
| url |
https://doaj.org/article/69d655df6fb54eb39a473438897f0433 |
| work_keys_str_mv |
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1718417198414823424 |