Serial interactome capture of the human cell nucleus

RNA-binding proteins are involved in the posttranscriptional regulation of a large number of cellular processes and several recent studies have sought to describe the extent of the RNA-binding proteome. Here, Conrad et al. describe serIC, a stringent approach they apply towards defining the RNA-bind...

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Autores principales: Thomas Conrad, Anne-Susann Albrecht, Veronica Rodrigues de Melo Costa, Sascha Sauer, David Meierhofer, Ulf Andersson Ørom
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2016
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Acceso en línea:https://doaj.org/article/69e220f40da44ba3bec616fc504d19de
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Sumario:RNA-binding proteins are involved in the posttranscriptional regulation of a large number of cellular processes and several recent studies have sought to describe the extent of the RNA-binding proteome. Here, Conrad et al. describe serIC, a stringent approach they apply towards defining the RNA-binding proteome of the mammalian nucleus.