Dynamics of the compartmentalized Streptomyces chromosome during metabolic differentiation

Streptomyces bacteria have a linear chromosome, with core genes located in the central region and gene clusters for specialized metabolite biosynthesis found in the ‘arms’. Here, Lioy et al. show that such chromosome structure correlates with genetic compartmentalization, and the onset of metabolic...

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Main Authors: Virginia S. Lioy, Jean-Noël Lorenzi, Soumaya Najah, Thibault Poinsignon, Hervé Leh, Corinne Saulnier, Bertrand Aigle, Sylvie Lautru, Annabelle Thibessard, Olivier Lespinet, Pierre Leblond, Yan Jaszczyszyn, Kevin Gorrichon, Nelle Varoquaux, Ivan Junier, Frédéric Boccard, Jean-Luc Pernodet, Stéphanie Bury-Moné
Format: article
Language:EN
Published: Nature Portfolio 2021
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Online Access:https://doaj.org/article/69ebdcca68044d26ae4c0c82ce1b8f3e
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