Poly(ADP-ribose) polymerase 1 accelerates vascular calcification by upregulating Runx2

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Poly(ADP-ribose) polymerase 1 accelerates vascular calcification by upregulating Runx2

Vascular calcification is a hallmark of end stage renal disease. Here, Cheng et al. show that poly(ADP-ribose) polymerase (PARP) activity is increased in calcified arteries in patients and uremic rats, and that PARP1 promotes vascular calcification by suppressing miR-204 expression via IL-6/STAT3 si...

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Detalles Bibliográficos
Autores principales:	Cheng Wang, Wenjing Xu, Jie An, Minglu Liang, Yiqing Li, Fengxiao Zhang, Qiangsong Tong, Kai Huang
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2019
Materias:	Science Q
Acceso en línea:	https://doaj.org/article/69ede5d3fbeb44789640a5683cea514a
Etiquetas:	Agregar Etiqueta Sin Etiquetas, Sea el primero en etiquetar este registro!

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