Neocortex and allocortex respond differentially to cellular stress in vitro and aging in vivo.
In Parkinson's and Alzheimer's diseases, the allocortex accumulates aggregated proteins such as synuclein and tau well before neocortex. We present a new high-throughput model of this topographic difference by microdissecting neocortex and allocortex from the postnatal rat and treating the...
Guardado en:
Autores principales: | Jessica M Posimo, Amanda M Titler, Hailey J H Choi, Ajay S Unnithan, Rehana K Leak |
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Formato: | article |
Lenguaje: | EN |
Publicado: |
Public Library of Science (PLoS)
2013
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Materias: | |
Acceso en línea: | https://doaj.org/article/69f333461b6541ccb32273d44f209d8a |
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