Metabolomic signatures associated with depression and predictors of antidepressant response in humans: A CAN-BIND-1 report

Caspani et al. report on sex-specific plasma lipoproteins predictive of response to two commonly used antidepressants. The authors show that lipoproteins belonging to the same main class but differing in size and density exhibit distinct associations with depression and with response to pharmacother...

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Autores principales: Giorgia Caspani, Gustavo Turecki, Raymond W. Lam, Roumen V. Milev, Benicio N. Frey, Glenda M. MacQueen, Daniel J. Müller, Susan Rotzinger, Sidney H. Kennedy, Jane A. Foster, Jonathan R. Swann
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Lenguaje:EN
Publicado: Nature Portfolio 2021
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Acceso en línea:https://doaj.org/article/69f53d425a4f4f34ab682a715bf2c822
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spelling oai:doaj.org-article:69f53d425a4f4f34ab682a715bf2c8222021-12-02T17:55:11ZMetabolomic signatures associated with depression and predictors of antidepressant response in humans: A CAN-BIND-1 report10.1038/s42003-021-02421-62399-3642https://doaj.org/article/69f53d425a4f4f34ab682a715bf2c8222021-07-01T00:00:00Zhttps://doi.org/10.1038/s42003-021-02421-6https://doaj.org/toc/2399-3642Caspani et al. report on sex-specific plasma lipoproteins predictive of response to two commonly used antidepressants. The authors show that lipoproteins belonging to the same main class but differing in size and density exhibit distinct associations with depression and with response to pharmacotherapy, highlighting the importance of evaluating lipoprotein subclass in depression research.Giorgia CaspaniGustavo TureckiRaymond W. LamRoumen V. MilevBenicio N. FreyGlenda M. MacQueenDaniel J. MüllerSusan RotzingerSidney H. KennedyJane A. FosterJonathan R. SwannNature PortfolioarticleBiology (General)QH301-705.5ENCommunications Biology, Vol 4, Iss 1, Pp 1-11 (2021)
institution DOAJ
collection DOAJ
language EN
topic Biology (General)
QH301-705.5
spellingShingle Biology (General)
QH301-705.5
Giorgia Caspani
Gustavo Turecki
Raymond W. Lam
Roumen V. Milev
Benicio N. Frey
Glenda M. MacQueen
Daniel J. Müller
Susan Rotzinger
Sidney H. Kennedy
Jane A. Foster
Jonathan R. Swann
Metabolomic signatures associated with depression and predictors of antidepressant response in humans: A CAN-BIND-1 report
description Caspani et al. report on sex-specific plasma lipoproteins predictive of response to two commonly used antidepressants. The authors show that lipoproteins belonging to the same main class but differing in size and density exhibit distinct associations with depression and with response to pharmacotherapy, highlighting the importance of evaluating lipoprotein subclass in depression research.
format article
author Giorgia Caspani
Gustavo Turecki
Raymond W. Lam
Roumen V. Milev
Benicio N. Frey
Glenda M. MacQueen
Daniel J. Müller
Susan Rotzinger
Sidney H. Kennedy
Jane A. Foster
Jonathan R. Swann
author_facet Giorgia Caspani
Gustavo Turecki
Raymond W. Lam
Roumen V. Milev
Benicio N. Frey
Glenda M. MacQueen
Daniel J. Müller
Susan Rotzinger
Sidney H. Kennedy
Jane A. Foster
Jonathan R. Swann
author_sort Giorgia Caspani
title Metabolomic signatures associated with depression and predictors of antidepressant response in humans: A CAN-BIND-1 report
title_short Metabolomic signatures associated with depression and predictors of antidepressant response in humans: A CAN-BIND-1 report
title_full Metabolomic signatures associated with depression and predictors of antidepressant response in humans: A CAN-BIND-1 report
title_fullStr Metabolomic signatures associated with depression and predictors of antidepressant response in humans: A CAN-BIND-1 report
title_full_unstemmed Metabolomic signatures associated with depression and predictors of antidepressant response in humans: A CAN-BIND-1 report
title_sort metabolomic signatures associated with depression and predictors of antidepressant response in humans: a can-bind-1 report
publisher Nature Portfolio
publishDate 2021
url https://doaj.org/article/69f53d425a4f4f34ab682a715bf2c822
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