REGN1908‐1909 monoclonal antibodies block Fel d 1 in cat allergic subjects: Translational pharmacokinetics and pharmacodynamics
Abstract REGN1908‐1909, a 1:1 cocktail of two fully human IgG4 monoclonal antibodies (mAbs), REGN1908 and REGN1909, is being evaluated for treatment of cat allergy. Both REGN1908 and REGN1909 bind to the dominant cat allergen, Fel d 1. Adults with cat allergy confirmed by skin prick test (SPT) were...
Guardado en:
Autores principales: | Mohamed A. Kamal, Robert Dingman, Claire Q. Wang, Ching‐Ha Lai, Manoj Rajadhyaksha, Michelle DeVeaux, Jamie M. Orengo, Allen Radin, John D. Davis |
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Formato: | article |
Lenguaje: | EN |
Publicado: |
Wiley
2021
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Materias: | |
Acceso en línea: | https://doaj.org/article/69f667aeb8fb4b37b8569c6e5adaa448 |
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