Stepwise maturation of the peptidyl transferase region of human mitoribosomes

Mammalian mitoribosomes feature dramatically reduced ribosomal RNAs and follow mitochondria specific assembly pathways. Here the authors describe the process of human mitochondrial ribosome maturation that results in the formation of the ribosomal active site region, including the peptidyl transfera...

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Autores principales:	Tea Lenarčič, Mateusz Jaskolowski, Marc Leibundgut, Alain Scaiola, Tanja Schönhut, Martin Saurer, Richard G. Lee, Oliver Rackham, Aleksandra Filipovska, Nenad Ban
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2021
Materias:	Science Q
Acceso en línea:	https://doaj.org/article/69f808b716604402b594c3fba4d45fcd
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spelling	oai:doaj.org-article:69f808b716604402b594c3fba4d45fcd2021-12-02T17:24:21ZStepwise maturation of the peptidyl transferase region of human mitoribosomes10.1038/s41467-021-23811-82041-1723https://doaj.org/article/69f808b716604402b594c3fba4d45fcd2021-06-01T00:00:00Zhttps://doi.org/10.1038/s41467-021-23811-8https://doaj.org/toc/2041-1723Mammalian mitoribosomes feature dramatically reduced ribosomal RNAs and follow mitochondria specific assembly pathways. Here the authors describe the process of human mitochondrial ribosome maturation that results in the formation of the ribosomal active site region, including the peptidyl transferase loop and the two tRNA-binding loops.Tea LenarčičMateusz JaskolowskiMarc LeibundgutAlain ScaiolaTanja SchönhutMartin SaurerRichard G. LeeOliver RackhamAleksandra FilipovskaNenad BanNature PortfolioarticleScienceQENNature Communications, Vol 12, Iss 1, Pp 1-8 (2021)
institution	DOAJ
collection	DOAJ
language	EN
topic	Science Q
spellingShingle	Science Q Tea Lenarčič Mateusz Jaskolowski Marc Leibundgut Alain Scaiola Tanja Schönhut Martin Saurer Richard G. Lee Oliver Rackham Aleksandra Filipovska Nenad Ban Stepwise maturation of the peptidyl transferase region of human mitoribosomes
description	Mammalian mitoribosomes feature dramatically reduced ribosomal RNAs and follow mitochondria specific assembly pathways. Here the authors describe the process of human mitochondrial ribosome maturation that results in the formation of the ribosomal active site region, including the peptidyl transferase loop and the two tRNA-binding loops.
format	article
author	Tea Lenarčič Mateusz Jaskolowski Marc Leibundgut Alain Scaiola Tanja Schönhut Martin Saurer Richard G. Lee Oliver Rackham Aleksandra Filipovska Nenad Ban
author_facet	Tea Lenarčič Mateusz Jaskolowski Marc Leibundgut Alain Scaiola Tanja Schönhut Martin Saurer Richard G. Lee Oliver Rackham Aleksandra Filipovska Nenad Ban
author_sort	Tea Lenarčič
title	Stepwise maturation of the peptidyl transferase region of human mitoribosomes
title_short	Stepwise maturation of the peptidyl transferase region of human mitoribosomes
title_full	Stepwise maturation of the peptidyl transferase region of human mitoribosomes
title_fullStr	Stepwise maturation of the peptidyl transferase region of human mitoribosomes
title_full_unstemmed	Stepwise maturation of the peptidyl transferase region of human mitoribosomes
title_sort	stepwise maturation of the peptidyl transferase region of human mitoribosomes
publisher	Nature Portfolio
publishDate	2021
url	https://doaj.org/article/69f808b716604402b594c3fba4d45fcd
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Stepwise maturation of the peptidyl transferase region of human mitoribosomes

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