The development of a reference database with the Topcon 3D OCT-1 Maestro

Michael Chaglasian,1 Murray Fingeret,2 Pinakin Gunvant Davey,3 Wei-Chieh Huang,4 Danny Leung,4 Edmund Ng,5 Charles A Reisman4 1Illinois Eye Institute, Illinois College of Optometry, Chicago, IL, USA; 2Department of Veterans Affairs, New York Harbor Health Care System, Brooklyn, NY, USA; 3School of...

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Autores principales:	Chaglasian M, Fingeret M, Davey PG, Huang WC, Leung D, Ng E, Reisman CA
Formato:	article
Lenguaje:	EN
Publicado:	Dove Medical Press 2018
Materias:	Spectral domain optical coherence tomography normal eyes Ophthalmology RE1-994
Acceso en línea:	https://doaj.org/article/69fb3db92fe549eb8696d6482c2428cc
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spelling	oai:doaj.org-article:69fb3db92fe549eb8696d6482c2428cc2021-12-02T07:30:02ZThe development of a reference database with the Topcon 3D OCT-1 Maestro1177-5483https://doaj.org/article/69fb3db92fe549eb8696d6482c2428cc2018-05-01T00:00:00Zhttps://www.dovepress.com/the-development-of-a-reference-database-with-the-topcon-3d-oct-1-maest-peer-reviewed-article-OPTHhttps://doaj.org/toc/1177-5483Michael Chaglasian,1 Murray Fingeret,2 Pinakin Gunvant Davey,3 Wei-Chieh Huang,4 Danny Leung,4 Edmund Ng,5 Charles A Reisman4 1Illinois Eye Institute, Illinois College of Optometry, Chicago, IL, USA; 2Department of Veterans Affairs, New York Harbor Health Care System, Brooklyn, NY, USA; 3School of Optometry, Western University of Health Sciences, Pomona, CA, USA; 4Topcon Healthcare Solutions Research and Development, Oakland, NJ, USA; 5Edmund Ng Consulting, LLC, Seattle, WA, USA Importance: The paper presents the range for measurements taken with a new spectral domain optical coherence tomography (OCT) device to establish a reference database for discrimination purposes. Objective: To report the range of thickness values for the new Topcon Maestro 3D OCT device with 2 scan size settings: the 12×9 mm wide field and 6×6 mm scans. Design: Prospective, multicenter cohort study conducted at 7 clinical sites across the USA. Setting: Primary eyecare clinics within academic, hospital, and private practice locations. Participants: Healthy volunteers; all enrolled participants underwent a complete ophthalmological examination to confirm healthy ocular status prior to being enrolled in the study. Main outcome measure: Average and 1st, 5th, 95th, and 99th percentile ranges for OCT parameters Early Treatment Diabetic Retinopathy Study macula full retinal thickness, ganglion cell + inner plexiform layer thickness (GCL + IPL), ganglion cell complex (GCC) thickness, circumpapillary retinal nerve fiber layer (cpRNFL) thickness. Results: Three hundred and ninety-nine eyes of 399 subjects were included in the analysis. Mean (SD) age was 46.3 (16.3) years (range 18–88 years). Forty-three percent of the subjects were male. Mean (SD) measurements (in μm) for the 12×9 mm wide scan were as follows: foveal thickness=237.079 (20.899), GCL + IPL=71.363 (5.924), GCC=105.949 (8.533), cpRNFL=104.720 (11.829); measurements for the 6×6 mm scans were as follows: foveal thickness=234.000 (20.657), GCL + IPL=71.726 (5.880), GCC=106.698 (9.094), cpRNFL=104.036 (11.341). Conclusion: The overall normal thickness values reported with Topcon 3D OCT-1 Maestro were like those studies with OCT from different manufactures. The reference limits at the 1st, 5th, 95th, and 99th percentile points establish the thresholds for the quantitative comparison of the cpRNFL and the macula in the human retina to a database of known healthy subjects. Keywords: spectral domain optical coherence tomography, normal eyes, 3D OCT-1 Maestro, macular measurements, circumpapillary retinal nerve fiber layer, optic discChaglasian MFingeret MDavey PGHuang WCLeung DNg EReisman CADove Medical PressarticleSpectral domain optical coherence tomographynormal eyesOphthalmologyRE1-994ENClinical Ophthalmology, Vol Volume 12, Pp 849-857 (2018)
institution	DOAJ
collection	DOAJ
language	EN
topic	Spectral domain optical coherence tomography normal eyes Ophthalmology RE1-994
spellingShingle	Spectral domain optical coherence tomography normal eyes Ophthalmology RE1-994 Chaglasian M Fingeret M Davey PG Huang WC Leung D Ng E Reisman CA The development of a reference database with the Topcon 3D OCT-1 Maestro
description	Michael Chaglasian,1 Murray Fingeret,2 Pinakin Gunvant Davey,3 Wei-Chieh Huang,4 Danny Leung,4 Edmund Ng,5 Charles A Reisman4 1Illinois Eye Institute, Illinois College of Optometry, Chicago, IL, USA; 2Department of Veterans Affairs, New York Harbor Health Care System, Brooklyn, NY, USA; 3School of Optometry, Western University of Health Sciences, Pomona, CA, USA; 4Topcon Healthcare Solutions Research and Development, Oakland, NJ, USA; 5Edmund Ng Consulting, LLC, Seattle, WA, USA Importance: The paper presents the range for measurements taken with a new spectral domain optical coherence tomography (OCT) device to establish a reference database for discrimination purposes. Objective: To report the range of thickness values for the new Topcon Maestro 3D OCT device with 2 scan size settings: the 12×9 mm wide field and 6×6 mm scans. Design: Prospective, multicenter cohort study conducted at 7 clinical sites across the USA. Setting: Primary eyecare clinics within academic, hospital, and private practice locations. Participants: Healthy volunteers; all enrolled participants underwent a complete ophthalmological examination to confirm healthy ocular status prior to being enrolled in the study. Main outcome measure: Average and 1st, 5th, 95th, and 99th percentile ranges for OCT parameters Early Treatment Diabetic Retinopathy Study macula full retinal thickness, ganglion cell + inner plexiform layer thickness (GCL + IPL), ganglion cell complex (GCC) thickness, circumpapillary retinal nerve fiber layer (cpRNFL) thickness. Results: Three hundred and ninety-nine eyes of 399 subjects were included in the analysis. Mean (SD) age was 46.3 (16.3) years (range 18–88 years). Forty-three percent of the subjects were male. Mean (SD) measurements (in μm) for the 12×9 mm wide scan were as follows: foveal thickness=237.079 (20.899), GCL + IPL=71.363 (5.924), GCC=105.949 (8.533), cpRNFL=104.720 (11.829); measurements for the 6×6 mm scans were as follows: foveal thickness=234.000 (20.657), GCL + IPL=71.726 (5.880), GCC=106.698 (9.094), cpRNFL=104.036 (11.341). Conclusion: The overall normal thickness values reported with Topcon 3D OCT-1 Maestro were like those studies with OCT from different manufactures. The reference limits at the 1st, 5th, 95th, and 99th percentile points establish the thresholds for the quantitative comparison of the cpRNFL and the macula in the human retina to a database of known healthy subjects. Keywords: spectral domain optical coherence tomography, normal eyes, 3D OCT-1 Maestro, macular measurements, circumpapillary retinal nerve fiber layer, optic disc
format	article
author	Chaglasian M Fingeret M Davey PG Huang WC Leung D Ng E Reisman CA
author_facet	Chaglasian M Fingeret M Davey PG Huang WC Leung D Ng E Reisman CA
author_sort	Chaglasian M
title	The development of a reference database with the Topcon 3D OCT-1 Maestro
title_short	The development of a reference database with the Topcon 3D OCT-1 Maestro
title_full	The development of a reference database with the Topcon 3D OCT-1 Maestro
title_fullStr	The development of a reference database with the Topcon 3D OCT-1 Maestro
title_full_unstemmed	The development of a reference database with the Topcon 3D OCT-1 Maestro
title_sort	development of a reference database with the topcon 3d oct-1 maestro
publisher	Dove Medical Press
publishDate	2018
url	https://doaj.org/article/69fb3db92fe549eb8696d6482c2428cc
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The development of a reference database with the Topcon 3D OCT-1 Maestro

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