Mechanisms involved in the beneficial effects of spironolactone after myocardial infarction.

Mechanisms involved in the beneficial effects of spironolactone after myocardial infarction.

<h4>Introduction</h4>Our objective was to analyze the effect of spironolactone on cardiac remodeling after experimental myocardial infarction (MI), assessed by matricellular proteins levels, cardiac collagen amount and distribution, myocardial tissue metalloproteinase inhibitor-1 (TIMP-1...

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Autores principales: Marcos F Minicucci, Priscila P dos Santos, Bruna P M Rafacho, Andrea F Gonçalves, Renata A C Silva, Fernanda Chiuso-Minicucci, Paula S Azevedo, Bertha F Polegato, Katashi Okoshi, Elenize J Pereira, Sergio A R Paiva, Leonardo A M Zornoff
Formato: article
Lenguaje:EN
Publicado: Public Library of Science (PLoS) 2013
Materias:
Medicine
R
Science
Q
Acceso en línea:https://doaj.org/article/6a04f357fc154422a656a7242ffda979
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