In situ precise electrospinning of medical glue fibers as nonsuture dural repair with high sealing capability and flexibility

Fu-Yan Lv,1,* Rui-Hua Dong,1,* Zhao-Jian Li,2,* Chong-Chong Qin,1 Xu Yan,1,3 Xiao-Xiao He,1 Yu Zhou,4 Shi-Ying Yan,1 Yun-Ze Long1,3 1Collaborative Innovation Center for Nanomaterials & Optoelectronic Devices, College of Physics, Qingdao University, 2Department of Neurosurgery, Affiliated Ho...

Descripción completa

Guardado en:

Detalles Bibliográficos
Autores principales:	Lv FY, Dong RH, Li ZJ, Qin CC, Yan X, He XX, Zhou Y, Yan SY, Long YZ
Formato:	article
Lenguaje:	EN
Publicado:	Dove Medical Press 2016
Materias:	Cyanoacrylates electrospun fibers In-situ repair dural Gas-assisted electrospinning apparatus Medicine (General) R5-920
Acceso en línea:	https://doaj.org/article/6a066d63555244eb8d909b26f94e7075
Etiquetas:	Agregar Etiqueta Sin Etiquetas, Sea el primero en etiquetar este registro!

id	oai:doaj.org-article:6a066d63555244eb8d909b26f94e7075
record_format	dspace
spelling	oai:doaj.org-article:6a066d63555244eb8d909b26f94e70752021-12-02T03:11:49ZIn situ precise electrospinning of medical glue fibers as nonsuture dural repair with high sealing capability and flexibility1178-2013https://doaj.org/article/6a066d63555244eb8d909b26f94e70752016-08-01T00:00:00Zhttps://www.dovepress.com/in-situ-precise-electrospinning-of-medical-glue-fibers-as-nonsuture-du-peer-reviewed-article-IJNhttps://doaj.org/toc/1178-2013Fu-Yan Lv,1,* Rui-Hua Dong,1,* Zhao-Jian Li,2,* Chong-Chong Qin,1 Xu Yan,1,3 Xiao-Xiao He,1 Yu Zhou,4 Shi-Ying Yan,1 Yun-Ze Long1,3 1Collaborative Innovation Center for Nanomaterials & Optoelectronic Devices, College of Physics, Qingdao University, 2Department of Neurosurgery, Affiliated Hospital of Qingdao University, 3Industrial Research Institute of Nonwovens & Technical Textiles, College of Textiles & Clothing, 4Medical College, Qingdao University, Qingdao, People’s Republic of China *These authors contributed equally to this work Purpose: In this work, we propose an in situ precise electrospinning of medical glue fibers onto dural wound for improving sealing capability, avoiding tissue adhesion, and saving time in dural repair.Methods: N-octyl-2-cyanoacrylate, a commercial tissue adhesive (medical glue), can be electrospun into ultrathin fibrous film with precise and homogeneous deposition by a gas-assisted electrospinning device.Results: The self-assembled N-octyl-2-cyanoacrylate film shows high compactness and flexibility owing to its fibrous structure. Simulation experiments on egg membranes and goat meninges demonstrated that this technology can repair small membrane defects quickly and efficiently.Conclusion: This method may have potential application in dural repair, for example, working as an effective supplementary technique for conventional dura suture. Keywords: cyanoacrylates, electrospun fibers, in situ repair dural, gas-assisted electrospinning apparatusLv FYDong RHLi ZJQin CCYan XHe XXZhou YYan SYLong YZDove Medical PressarticleCyanoacrylateselectrospun fibersIn-situ repair duralGas-assisted electrospinning apparatusMedicine (General)R5-920ENInternational Journal of Nanomedicine, Vol Volume 11, Pp 4213-4220 (2016)
institution	DOAJ
collection	DOAJ
language	EN
topic	Cyanoacrylates electrospun fibers In-situ repair dural Gas-assisted electrospinning apparatus Medicine (General) R5-920
spellingShingle	Cyanoacrylates electrospun fibers In-situ repair dural Gas-assisted electrospinning apparatus Medicine (General) R5-920 Lv FY Dong RH Li ZJ Qin CC Yan X He XX Zhou Y Yan SY Long YZ In situ precise electrospinning of medical glue fibers as nonsuture dural repair with high sealing capability and flexibility
description	Fu-Yan Lv,1,* Rui-Hua Dong,1,* Zhao-Jian Li,2,* Chong-Chong Qin,1 Xu Yan,1,3 Xiao-Xiao He,1 Yu Zhou,4 Shi-Ying Yan,1 Yun-Ze Long1,3 1Collaborative Innovation Center for Nanomaterials & Optoelectronic Devices, College of Physics, Qingdao University, 2Department of Neurosurgery, Affiliated Hospital of Qingdao University, 3Industrial Research Institute of Nonwovens & Technical Textiles, College of Textiles & Clothing, 4Medical College, Qingdao University, Qingdao, People’s Republic of China *These authors contributed equally to this work Purpose: In this work, we propose an in situ precise electrospinning of medical glue fibers onto dural wound for improving sealing capability, avoiding tissue adhesion, and saving time in dural repair.Methods: N-octyl-2-cyanoacrylate, a commercial tissue adhesive (medical glue), can be electrospun into ultrathin fibrous film with precise and homogeneous deposition by a gas-assisted electrospinning device.Results: The self-assembled N-octyl-2-cyanoacrylate film shows high compactness and flexibility owing to its fibrous structure. Simulation experiments on egg membranes and goat meninges demonstrated that this technology can repair small membrane defects quickly and efficiently.Conclusion: This method may have potential application in dural repair, for example, working as an effective supplementary technique for conventional dura suture. Keywords: cyanoacrylates, electrospun fibers, in situ repair dural, gas-assisted electrospinning apparatus
format	article
author	Lv FY Dong RH Li ZJ Qin CC Yan X He XX Zhou Y Yan SY Long YZ
author_facet	Lv FY Dong RH Li ZJ Qin CC Yan X He XX Zhou Y Yan SY Long YZ
author_sort	Lv FY
title	In situ precise electrospinning of medical glue fibers as nonsuture dural repair with high sealing capability and flexibility
title_short	In situ precise electrospinning of medical glue fibers as nonsuture dural repair with high sealing capability and flexibility
title_full	In situ precise electrospinning of medical glue fibers as nonsuture dural repair with high sealing capability and flexibility
title_fullStr	In situ precise electrospinning of medical glue fibers as nonsuture dural repair with high sealing capability and flexibility
title_full_unstemmed	In situ precise electrospinning of medical glue fibers as nonsuture dural repair with high sealing capability and flexibility
title_sort	in situ precise electrospinning of medical glue fibers as nonsuture dural repair with high sealing capability and flexibility
publisher	Dove Medical Press
publishDate	2016
url	https://doaj.org/article/6a066d63555244eb8d909b26f94e7075
work_keys_str_mv	AT lvfy insitupreciseelectrospinningofmedicalgluefibersasnonsutureduralrepairwithhighsealingcapabilityandflexibility AT dongrh insitupreciseelectrospinningofmedicalgluefibersasnonsutureduralrepairwithhighsealingcapabilityandflexibility AT lizj insitupreciseelectrospinningofmedicalgluefibersasnonsutureduralrepairwithhighsealingcapabilityandflexibility AT qincc insitupreciseelectrospinningofmedicalgluefibersasnonsutureduralrepairwithhighsealingcapabilityandflexibility AT yanx insitupreciseelectrospinningofmedicalgluefibersasnonsutureduralrepairwithhighsealingcapabilityandflexibility AT hexx insitupreciseelectrospinningofmedicalgluefibersasnonsutureduralrepairwithhighsealingcapabilityandflexibility AT zhouy insitupreciseelectrospinningofmedicalgluefibersasnonsutureduralrepairwithhighsealingcapabilityandflexibility AT yansy insitupreciseelectrospinningofmedicalgluefibersasnonsutureduralrepairwithhighsealingcapabilityandflexibility AT longyz insitupreciseelectrospinningofmedicalgluefibersasnonsutureduralrepairwithhighsealingcapabilityandflexibility
_version_	1718401858681176064

In situ precise electrospinning of medical glue fibers as nonsuture dural repair with high sealing capability and flexibility

Ejemplares similares