TET3 prevents terminal differentiation of adult NSCs by a non-catalytic action at Snrpn

TET3 prevents terminal differentiation of adult NSCs by a non-catalytic action at Snrpn

The potential role of TET proteins in adult neurogenesis is unknown. In this study, authors show that TET3 is essentially required for the maintenance of the NSC pool in the adult subventricular zone niche by preventing premature differentiation of NSCs, via direct binding and repression of the pate...

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Autores principales: Raquel Montalbán-Loro, Anna Lozano-Ureña, Mitsuteru Ito, Christel Krueger, Wolf Reik, Anne C. Ferguson-Smith, Sacri R. Ferrón
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2019
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Science
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Acceso en línea:https://doaj.org/article/6a16a9a8341a4206bf85aaf5f9a6ae31
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