The state of lipoperoxidation processes in boys with obesity

The problem of obesity is extremely relevant for modern medical science and healthcare, and child and adolescent obesity deserves special attention. It seems to be interesting to trace the interrelation of pathological processes in obesity in the form of metabolic disorders at the level of the organ...

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Autores principales:	M. A. Darenskaya, O. A. Gavrilova, L. A. Grebenkina, O. V. Kravtsova, L. V. Natyaganova
Formato:	article
Lenguaje:	RU
Publicado:	Scientific Сentre for Family Health and Human Reproduction Problems 2017
Materias:	lipid peroxidation adolescents obesity Science Q
Acceso en línea:	https://doaj.org/article/6a1bf148ac5f4a18b53f552a16fc859d
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spelling	oai:doaj.org-article:6a1bf148ac5f4a18b53f552a16fc859d2021-11-23T06:14:38ZThe state of lipoperoxidation processes in boys with obesity2541-94202587-959610.12737/article_5a3a0d764250a4.87243362https://doaj.org/article/6a1bf148ac5f4a18b53f552a16fc859d2017-09-01T00:00:00Zhttps://www.actabiomedica.ru/jour/article/view/502https://doaj.org/toc/2541-9420https://doaj.org/toc/2587-9596The problem of obesity is extremely relevant for modern medical science and healthcare, and child and adolescent obesity deserves special attention. It seems to be interesting to trace the interrelation of pathological processes in obesity in the form of metabolic disorders at the level of the organism and at the cell level - disorders in the system of lipid peroxidation. Studies in adolescent boys are relevant, as there has been a general increase in the incidence in this age category. The purpose of the research was to study the state of the system "lipid peroxidation - antioxidant protection" in adolescent boys with exogenous-constitutional obesity. 19 adolescent boys with obesity were examined in comparison with the control group. Spectrophotometric and fluorometric methods of examination were used. An increase in the level of secondary lipid peroxidation products - ketodienes and conjugated trienes (1.65 times) - was revealed in adolescent boys with obesity. In the antioxidant defense system, differences in this group included reduced values of α-tocopherol (1.42 times), retinol (1.51 times) and superoxide dismutase activity (1.19 times), in the absence of statistically significant changes in the total antioxidant activity (AOA) in blood and components of glutathione status. The revealed disorders allow to recommend the complex therapy including prescription of antioxidants and medicines directed on normalization of lipid exchange at the given category of patients.M. A. DarenskayaO. A. GavrilovaL. A. GrebenkinaO. V. KravtsovaL. V. NatyaganovaScientific Сentre for Family Health and Human Reproduction Problemsarticlelipid peroxidationadolescentsobesityScienceQRUActa Biomedica Scientifica, Vol 2, Iss 5(2), Pp 28-32 (2017)
institution	DOAJ
collection	DOAJ
language	RU
topic	lipid peroxidation adolescents obesity Science Q
spellingShingle	lipid peroxidation adolescents obesity Science Q M. A. Darenskaya O. A. Gavrilova L. A. Grebenkina O. V. Kravtsova L. V. Natyaganova The state of lipoperoxidation processes in boys with obesity
description	The problem of obesity is extremely relevant for modern medical science and healthcare, and child and adolescent obesity deserves special attention. It seems to be interesting to trace the interrelation of pathological processes in obesity in the form of metabolic disorders at the level of the organism and at the cell level - disorders in the system of lipid peroxidation. Studies in adolescent boys are relevant, as there has been a general increase in the incidence in this age category. The purpose of the research was to study the state of the system "lipid peroxidation - antioxidant protection" in adolescent boys with exogenous-constitutional obesity. 19 adolescent boys with obesity were examined in comparison with the control group. Spectrophotometric and fluorometric methods of examination were used. An increase in the level of secondary lipid peroxidation products - ketodienes and conjugated trienes (1.65 times) - was revealed in adolescent boys with obesity. In the antioxidant defense system, differences in this group included reduced values of α-tocopherol (1.42 times), retinol (1.51 times) and superoxide dismutase activity (1.19 times), in the absence of statistically significant changes in the total antioxidant activity (AOA) in blood and components of glutathione status. The revealed disorders allow to recommend the complex therapy including prescription of antioxidants and medicines directed on normalization of lipid exchange at the given category of patients.
format	article
author	M. A. Darenskaya O. A. Gavrilova L. A. Grebenkina O. V. Kravtsova L. V. Natyaganova
author_facet	M. A. Darenskaya O. A. Gavrilova L. A. Grebenkina O. V. Kravtsova L. V. Natyaganova
author_sort	M. A. Darenskaya
title	The state of lipoperoxidation processes in boys with obesity
title_short	The state of lipoperoxidation processes in boys with obesity
title_full	The state of lipoperoxidation processes in boys with obesity
title_fullStr	The state of lipoperoxidation processes in boys with obesity
title_full_unstemmed	The state of lipoperoxidation processes in boys with obesity
title_sort	state of lipoperoxidation processes in boys with obesity
publisher	Scientific Сentre for Family Health and Human Reproduction Problems
publishDate	2017
url	https://doaj.org/article/6a1bf148ac5f4a18b53f552a16fc859d
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The state of lipoperoxidation processes in boys with obesity

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