Results of the study of the immunogenic activity of cell envelopes of Francisella tularensis different subspicies (Report 2)

The effect of cell envelopes preparations of four subspecies of Francisella tularensis, derived from urea lysates of tularemia microbe on cytokine production by immunocompetent cells of experimental animals has been studied. Stimulating influence of F. tularensis cell envelopes preparations on cytok...

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Autores principales:	A. V. Korneva, V. B. Nikolaev, K. Yu. Yastremskaya, E. Yu. Markov, V. V. Voytkova, S. Yu. Solovyov, Yu. O. Popova, A. V. Mazepa, T. A. Ivanova, V. S. Polovinkina
Formato:	article
Lenguaje:	RU
Publicado:	Scientific Сentre for Family Health and Human Reproduction Problems 2015
Materias:	tularemia francisella tularensis cell membranes cytokines immune cells vaccines Science Q
Acceso en línea:	https://doaj.org/article/6a29c8b8dff24acaa41a129c3dacfa70
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spelling	oai:doaj.org-article:6a29c8b8dff24acaa41a129c3dacfa702021-11-23T06:14:32ZResults of the study of the immunogenic activity of cell envelopes of Francisella tularensis different subspicies (Report 2)2541-94202587-9596https://doaj.org/article/6a29c8b8dff24acaa41a129c3dacfa702015-02-01T00:00:00Zhttps://www.actabiomedica.ru/jour/article/view/13https://doaj.org/toc/2541-9420https://doaj.org/toc/2587-9596The effect of cell envelopes preparations of four subspecies of Francisella tularensis, derived from urea lysates of tularemia microbe on cytokine production by immunocompetent cells of experimental animals has been studied. Stimulating influence of F. tularensis cell envelopes preparations on cytokine synthesis on the 7th day after inoculation was shown. The results showed that the cell envelopes of different subspecies F. tularensis have different stimulatory effect on the production of proinflammatory cytokines and growth factors GM-CSF and G-CSF, further defining the immune system of host.The results allow to consider cell envelopes preparations of F. tularensis as constituent component in the development of subunit vaccines.A. V. KornevaV. B. NikolaevK. Yu. YastremskayaE. Yu. MarkovV. V. VoytkovaS. Yu. SolovyovYu. O. PopovaA. V. MazepaT. A. IvanovaV. S. PolovinkinaScientific Сentre for Family Health and Human Reproduction Problemsarticletularemiafrancisella tularensiscell membranescytokinesimmune cellsvaccinesfrancisella tularensisScienceQRUActa Biomedica Scientifica, Vol 0, Iss 1, Pp 63-66 (2015)
institution	DOAJ
collection	DOAJ
language	RU
topic	tularemia francisella tularensis cell membranes cytokines immune cells vaccines francisella tularensis Science Q
spellingShingle	tularemia francisella tularensis cell membranes cytokines immune cells vaccines francisella tularensis Science Q A. V. Korneva V. B. Nikolaev K. Yu. Yastremskaya E. Yu. Markov V. V. Voytkova S. Yu. Solovyov Yu. O. Popova A. V. Mazepa T. A. Ivanova V. S. Polovinkina Results of the study of the immunogenic activity of cell envelopes of Francisella tularensis different subspicies (Report 2)
description	The effect of cell envelopes preparations of four subspecies of Francisella tularensis, derived from urea lysates of tularemia microbe on cytokine production by immunocompetent cells of experimental animals has been studied. Stimulating influence of F. tularensis cell envelopes preparations on cytokine synthesis on the 7th day after inoculation was shown. The results showed that the cell envelopes of different subspecies F. tularensis have different stimulatory effect on the production of proinflammatory cytokines and growth factors GM-CSF and G-CSF, further defining the immune system of host.The results allow to consider cell envelopes preparations of F. tularensis as constituent component in the development of subunit vaccines.
format	article
author	A. V. Korneva V. B. Nikolaev K. Yu. Yastremskaya E. Yu. Markov V. V. Voytkova S. Yu. Solovyov Yu. O. Popova A. V. Mazepa T. A. Ivanova V. S. Polovinkina
author_facet	A. V. Korneva V. B. Nikolaev K. Yu. Yastremskaya E. Yu. Markov V. V. Voytkova S. Yu. Solovyov Yu. O. Popova A. V. Mazepa T. A. Ivanova V. S. Polovinkina
author_sort	A. V. Korneva
title	Results of the study of the immunogenic activity of cell envelopes of Francisella tularensis different subspicies (Report 2)
title_short	Results of the study of the immunogenic activity of cell envelopes of Francisella tularensis different subspicies (Report 2)
title_full	Results of the study of the immunogenic activity of cell envelopes of Francisella tularensis different subspicies (Report 2)
title_fullStr	Results of the study of the immunogenic activity of cell envelopes of Francisella tularensis different subspicies (Report 2)
title_full_unstemmed	Results of the study of the immunogenic activity of cell envelopes of Francisella tularensis different subspicies (Report 2)
title_sort	results of the study of the immunogenic activity of cell envelopes of francisella tularensis different subspicies (report 2)
publisher	Scientific Сentre for Family Health and Human Reproduction Problems
publishDate	2015
url	https://doaj.org/article/6a29c8b8dff24acaa41a129c3dacfa70
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Results of the study of the immunogenic activity of cell envelopes of Francisella tularensis different subspicies (Report 2)

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