VCAM1 acts in parallel with CD69 and is required for the initiation of oligodendrocyte myelination

The vascular cell adhesion molecule VCAM1 plays a role in the immune system but is also expressed in oligodendrocytes. Here, the authors find VCAM1 interacts with neuronal α4 integrin to regulate oligodendrocyte differentiation and thereby myelination, an effect mediated by downstream CD69 signallin...

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Autores principales:	Yuki Miyamoto, Tomohiro Torii, Akito Tanoue, Junji Yamauchi
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2016
Materias:	Science Q
Acceso en línea:	https://doaj.org/article/6a2afea3d1d04a72930e6e9336c933d2
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spelling	oai:doaj.org-article:6a2afea3d1d04a72930e6e9336c933d22021-12-02T14:40:15ZVCAM1 acts in parallel with CD69 and is required for the initiation of oligodendrocyte myelination10.1038/ncomms134782041-1723https://doaj.org/article/6a2afea3d1d04a72930e6e9336c933d22016-11-01T00:00:00Zhttps://doi.org/10.1038/ncomms13478https://doaj.org/toc/2041-1723The vascular cell adhesion molecule VCAM1 plays a role in the immune system but is also expressed in oligodendrocytes. Here, the authors find VCAM1 interacts with neuronal α4 integrin to regulate oligodendrocyte differentiation and thereby myelination, an effect mediated by downstream CD69 signalling.Yuki MiyamotoTomohiro ToriiAkito TanoueJunji YamauchiNature PortfolioarticleScienceQENNature Communications, Vol 7, Iss 1, Pp 1-16 (2016)
institution	DOAJ
collection	DOAJ
language	EN
topic	Science Q
spellingShingle	Science Q Yuki Miyamoto Tomohiro Torii Akito Tanoue Junji Yamauchi VCAM1 acts in parallel with CD69 and is required for the initiation of oligodendrocyte myelination
description	The vascular cell adhesion molecule VCAM1 plays a role in the immune system but is also expressed in oligodendrocytes. Here, the authors find VCAM1 interacts with neuronal α4 integrin to regulate oligodendrocyte differentiation and thereby myelination, an effect mediated by downstream CD69 signalling.
format	article
author	Yuki Miyamoto Tomohiro Torii Akito Tanoue Junji Yamauchi
author_facet	Yuki Miyamoto Tomohiro Torii Akito Tanoue Junji Yamauchi
author_sort	Yuki Miyamoto
title	VCAM1 acts in parallel with CD69 and is required for the initiation of oligodendrocyte myelination
title_short	VCAM1 acts in parallel with CD69 and is required for the initiation of oligodendrocyte myelination
title_full	VCAM1 acts in parallel with CD69 and is required for the initiation of oligodendrocyte myelination
title_fullStr	VCAM1 acts in parallel with CD69 and is required for the initiation of oligodendrocyte myelination
title_full_unstemmed	VCAM1 acts in parallel with CD69 and is required for the initiation of oligodendrocyte myelination
title_sort	vcam1 acts in parallel with cd69 and is required for the initiation of oligodendrocyte myelination
publisher	Nature Portfolio
publishDate	2016
url	https://doaj.org/article/6a2afea3d1d04a72930e6e9336c933d2
work_keys_str_mv	AT yukimiyamoto vcam1actsinparallelwithcd69andisrequiredfortheinitiationofoligodendrocytemyelination AT tomohirotorii vcam1actsinparallelwithcd69andisrequiredfortheinitiationofoligodendrocytemyelination AT akitotanoue vcam1actsinparallelwithcd69andisrequiredfortheinitiationofoligodendrocytemyelination AT junjiyamauchi vcam1actsinparallelwithcd69andisrequiredfortheinitiationofoligodendrocytemyelination
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VCAM1 acts in parallel with CD69 and is required for the initiation of oligodendrocyte myelination

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