Activated CD8+ T cell extracellular vesicles prevent tumour progression by targeting of lesional mesenchymal cells

Immune cells have an important role in tumour progression. Here, the authors show that extracellular vesicles from activated CD8+ T cells attenuate tumour progression by depletion of mesenchymal tumour stromal cells.

Guardado en:

Detalles Bibliográficos
Autores principales:	Naohiro Seo, Yoshitaka Shirakura, Yoshiro Tahara, Fumiyasu Momose, Naozumi Harada, Hiroaki Ikeda, Kazunari Akiyoshi, Hiroshi Shiku
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2018
Materias:	Science Q
Acceso en línea:	https://doaj.org/article/6a2cc30b31e1417ba6551dd38e924e4a
Etiquetas:	Agregar Etiqueta Sin Etiquetas, Sea el primero en etiquetar este registro!

id	oai:doaj.org-article:6a2cc30b31e1417ba6551dd38e924e4a
record_format	dspace
spelling	oai:doaj.org-article:6a2cc30b31e1417ba6551dd38e924e4a2021-12-02T16:49:20ZActivated CD8+ T cell extracellular vesicles prevent tumour progression by targeting of lesional mesenchymal cells10.1038/s41467-018-02865-12041-1723https://doaj.org/article/6a2cc30b31e1417ba6551dd38e924e4a2018-01-01T00:00:00Zhttps://doi.org/10.1038/s41467-018-02865-1https://doaj.org/toc/2041-1723Immune cells have an important role in tumour progression. Here, the authors show that extracellular vesicles from activated CD8+ T cells attenuate tumour progression by depletion of mesenchymal tumour stromal cells.Naohiro SeoYoshitaka ShirakuraYoshiro TaharaFumiyasu MomoseNaozumi HaradaHiroaki IkedaKazunari AkiyoshiHiroshi ShikuNature PortfolioarticleScienceQENNature Communications, Vol 9, Iss 1, Pp 1-11 (2018)
institution	DOAJ
collection	DOAJ
language	EN
topic	Science Q
spellingShingle	Science Q Naohiro Seo Yoshitaka Shirakura Yoshiro Tahara Fumiyasu Momose Naozumi Harada Hiroaki Ikeda Kazunari Akiyoshi Hiroshi Shiku Activated CD8+ T cell extracellular vesicles prevent tumour progression by targeting of lesional mesenchymal cells
description	Immune cells have an important role in tumour progression. Here, the authors show that extracellular vesicles from activated CD8+ T cells attenuate tumour progression by depletion of mesenchymal tumour stromal cells.
format	article
author	Naohiro Seo Yoshitaka Shirakura Yoshiro Tahara Fumiyasu Momose Naozumi Harada Hiroaki Ikeda Kazunari Akiyoshi Hiroshi Shiku
author_facet	Naohiro Seo Yoshitaka Shirakura Yoshiro Tahara Fumiyasu Momose Naozumi Harada Hiroaki Ikeda Kazunari Akiyoshi Hiroshi Shiku
author_sort	Naohiro Seo
title	Activated CD8+ T cell extracellular vesicles prevent tumour progression by targeting of lesional mesenchymal cells
title_short	Activated CD8+ T cell extracellular vesicles prevent tumour progression by targeting of lesional mesenchymal cells
title_full	Activated CD8+ T cell extracellular vesicles prevent tumour progression by targeting of lesional mesenchymal cells
title_fullStr	Activated CD8+ T cell extracellular vesicles prevent tumour progression by targeting of lesional mesenchymal cells
title_full_unstemmed	Activated CD8+ T cell extracellular vesicles prevent tumour progression by targeting of lesional mesenchymal cells
title_sort	activated cd8+ t cell extracellular vesicles prevent tumour progression by targeting of lesional mesenchymal cells
publisher	Nature Portfolio
publishDate	2018
url	https://doaj.org/article/6a2cc30b31e1417ba6551dd38e924e4a
work_keys_str_mv	AT naohiroseo activatedcd8tcellextracellularvesiclespreventtumourprogressionbytargetingoflesionalmesenchymalcells AT yoshitakashirakura activatedcd8tcellextracellularvesiclespreventtumourprogressionbytargetingoflesionalmesenchymalcells AT yoshirotahara activatedcd8tcellextracellularvesiclespreventtumourprogressionbytargetingoflesionalmesenchymalcells AT fumiyasumomose activatedcd8tcellextracellularvesiclespreventtumourprogressionbytargetingoflesionalmesenchymalcells AT naozumiharada activatedcd8tcellextracellularvesiclespreventtumourprogressionbytargetingoflesionalmesenchymalcells AT hiroakiikeda activatedcd8tcellextracellularvesiclespreventtumourprogressionbytargetingoflesionalmesenchymalcells AT kazunariakiyoshi activatedcd8tcellextracellularvesiclespreventtumourprogressionbytargetingoflesionalmesenchymalcells AT hiroshishiku activatedcd8tcellextracellularvesiclespreventtumourprogressionbytargetingoflesionalmesenchymalcells
_version_	1718383338828333056

Activated CD8+ T cell extracellular vesicles prevent tumour progression by targeting of lesional mesenchymal cells

Ejemplares similares