Utilization of rare codon-rich markers for screening amino acid overproducers
Current toxic analogues-based amino acid overproducer screening method cannot provide accuracy, sensitivity and high throughput simultaneously. Here, the authors use rare codon rich marker for the selection of overproducers of multiple amino acids from random mutation libraries of E. coli and C. glu...
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Nature Portfolio
2018
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oai:doaj.org-article:6a375f7309ef48ea9131810368d1e5952021-12-02T14:39:07ZUtilization of rare codon-rich markers for screening amino acid overproducers10.1038/s41467-018-05830-02041-1723https://doaj.org/article/6a375f7309ef48ea9131810368d1e5952018-09-01T00:00:00Zhttps://doi.org/10.1038/s41467-018-05830-0https://doaj.org/toc/2041-1723Current toxic analogues-based amino acid overproducer screening method cannot provide accuracy, sensitivity and high throughput simultaneously. Here, the authors use rare codon rich marker for the selection of overproducers of multiple amino acids from random mutation libraries of E. coli and C. glutamicum.Bo ZhengXiaoyan MaNing WangTingting DingLiwei GuoXiaorong ZhangYu YangChun LiYi-Xin HuoNature PortfolioarticleScienceQENNature Communications, Vol 9, Iss 1, Pp 1-11 (2018) |
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Science Q Bo Zheng Xiaoyan Ma Ning Wang Tingting Ding Liwei Guo Xiaorong Zhang Yu Yang Chun Li Yi-Xin Huo Utilization of rare codon-rich markers for screening amino acid overproducers |
description |
Current toxic analogues-based amino acid overproducer screening method cannot provide accuracy, sensitivity and high throughput simultaneously. Here, the authors use rare codon rich marker for the selection of overproducers of multiple amino acids from random mutation libraries of E. coli and C. glutamicum. |
format |
article |
author |
Bo Zheng Xiaoyan Ma Ning Wang Tingting Ding Liwei Guo Xiaorong Zhang Yu Yang Chun Li Yi-Xin Huo |
author_facet |
Bo Zheng Xiaoyan Ma Ning Wang Tingting Ding Liwei Guo Xiaorong Zhang Yu Yang Chun Li Yi-Xin Huo |
author_sort |
Bo Zheng |
title |
Utilization of rare codon-rich markers for screening amino acid overproducers |
title_short |
Utilization of rare codon-rich markers for screening amino acid overproducers |
title_full |
Utilization of rare codon-rich markers for screening amino acid overproducers |
title_fullStr |
Utilization of rare codon-rich markers for screening amino acid overproducers |
title_full_unstemmed |
Utilization of rare codon-rich markers for screening amino acid overproducers |
title_sort |
utilization of rare codon-rich markers for screening amino acid overproducers |
publisher |
Nature Portfolio |
publishDate |
2018 |
url |
https://doaj.org/article/6a375f7309ef48ea9131810368d1e595 |
work_keys_str_mv |
AT bozheng utilizationofrarecodonrichmarkersforscreeningaminoacidoverproducers AT xiaoyanma utilizationofrarecodonrichmarkersforscreeningaminoacidoverproducers AT ningwang utilizationofrarecodonrichmarkersforscreeningaminoacidoverproducers AT tingtingding utilizationofrarecodonrichmarkersforscreeningaminoacidoverproducers AT liweiguo utilizationofrarecodonrichmarkersforscreeningaminoacidoverproducers AT xiaorongzhang utilizationofrarecodonrichmarkersforscreeningaminoacidoverproducers AT yuyang utilizationofrarecodonrichmarkersforscreeningaminoacidoverproducers AT chunli utilizationofrarecodonrichmarkersforscreeningaminoacidoverproducers AT yixinhuo utilizationofrarecodonrichmarkersforscreeningaminoacidoverproducers |
_version_ |
1718390718120067072 |