Superenhancer–transcription factor regulatory network in malignant tumors

This study aims to identify superenhancer (SE)–transcriptional factor (TF) regulatory network related to eight common malignant tumors based on ChIP-seq data modified by histone H3K27ac in the enhancer region of the SRA database.

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Autores principales: Liang Yuan, Li Linlin, Xin Tian, Li Binru, Zhang Dalin
Formato: article
Lenguaje:EN
Publicado: De Gruyter 2021
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R
Acceso en línea:https://doaj.org/article/6a46785b4db64d48bb07bc8d22b74050
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spelling oai:doaj.org-article:6a46785b4db64d48bb07bc8d22b740502021-12-05T14:10:55ZSuperenhancer–transcription factor regulatory network in malignant tumors2391-546310.1515/med-2021-0326https://doaj.org/article/6a46785b4db64d48bb07bc8d22b740502021-10-01T00:00:00Zhttps://doi.org/10.1515/med-2021-0326https://doaj.org/toc/2391-5463This study aims to identify superenhancer (SE)–transcriptional factor (TF) regulatory network related to eight common malignant tumors based on ChIP-seq data modified by histone H3K27ac in the enhancer region of the SRA database.Liang YuanLi LinlinXin TianLi BinruZhang DalinDe Gruyterarticlemalignant tumorssuper enhancerstranscription factorschip-seqrna-seqcore regulatory circuitrysuperenhancer–transcription factor regulatory networkMedicineRENOpen Medicine, Vol 16, Iss 1, Pp 1564-1582 (2021)
institution DOAJ
collection DOAJ
language EN
topic malignant tumors
super enhancers
transcription factors
chip-seq
rna-seq
core regulatory circuitry
superenhancer–transcription factor regulatory network
Medicine
R
spellingShingle malignant tumors
super enhancers
transcription factors
chip-seq
rna-seq
core regulatory circuitry
superenhancer–transcription factor regulatory network
Medicine
R
Liang Yuan
Li Linlin
Xin Tian
Li Binru
Zhang Dalin
Superenhancer–transcription factor regulatory network in malignant tumors
description This study aims to identify superenhancer (SE)–transcriptional factor (TF) regulatory network related to eight common malignant tumors based on ChIP-seq data modified by histone H3K27ac in the enhancer region of the SRA database.
format article
author Liang Yuan
Li Linlin
Xin Tian
Li Binru
Zhang Dalin
author_facet Liang Yuan
Li Linlin
Xin Tian
Li Binru
Zhang Dalin
author_sort Liang Yuan
title Superenhancer–transcription factor regulatory network in malignant tumors
title_short Superenhancer–transcription factor regulatory network in malignant tumors
title_full Superenhancer–transcription factor regulatory network in malignant tumors
title_fullStr Superenhancer–transcription factor regulatory network in malignant tumors
title_full_unstemmed Superenhancer–transcription factor regulatory network in malignant tumors
title_sort superenhancer–transcription factor regulatory network in malignant tumors
publisher De Gruyter
publishDate 2021
url https://doaj.org/article/6a46785b4db64d48bb07bc8d22b74050
work_keys_str_mv AT liangyuan superenhancertranscriptionfactorregulatorynetworkinmalignanttumors
AT lilinlin superenhancertranscriptionfactorregulatorynetworkinmalignanttumors
AT xintian superenhancertranscriptionfactorregulatorynetworkinmalignanttumors
AT libinru superenhancertranscriptionfactorregulatorynetworkinmalignanttumors
AT zhangdalin superenhancertranscriptionfactorregulatorynetworkinmalignanttumors
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