Non-invasive molecularly-specific millimeter-resolution manipulation of brain circuits by ultrasound-mediated aggregation and uncaging of drug carriers

Non-invasive manipulation of brain circuits with molecular and spatial specificity could revolutionize the treatment of brain disorders. Here, the authors remotely concentrate and deliver drugs to focal brain regions without compromising the blood-brain barrier using novel ultrasound sequences and d...

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Autores principales:	Mehmet S. Ozdas, Aagam S. Shah, Paul M. Johnson, Nisheet Patel, Markus Marks, Tansel Baran Yasar, Urs Stalder, Laurent Bigler, Wolfger von der Behrens, Shashank R. Sirsi, Mehmet Fatih Yanik
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2020
Materias:	Science Q
Acceso en línea:	https://doaj.org/article/6a492392efd7456ea115ebf1a7ce1edc
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spelling	oai:doaj.org-article:6a492392efd7456ea115ebf1a7ce1edc2021-12-02T17:18:12ZNon-invasive molecularly-specific millimeter-resolution manipulation of brain circuits by ultrasound-mediated aggregation and uncaging of drug carriers10.1038/s41467-020-18059-72041-1723https://doaj.org/article/6a492392efd7456ea115ebf1a7ce1edc2020-10-01T00:00:00Zhttps://doi.org/10.1038/s41467-020-18059-7https://doaj.org/toc/2041-1723Non-invasive manipulation of brain circuits with molecular and spatial specificity could revolutionize the treatment of brain disorders. Here, the authors remotely concentrate and deliver drugs to focal brain regions without compromising the blood-brain barrier using novel ultrasound sequences and drug carriers.Mehmet S. OzdasAagam S. ShahPaul M. JohnsonNisheet PatelMarkus MarksTansel Baran YasarUrs StalderLaurent BiglerWolfger von der BehrensShashank R. SirsiMehmet Fatih YanikNature PortfolioarticleScienceQENNature Communications, Vol 11, Iss 1, Pp 1-15 (2020)
institution	DOAJ
collection	DOAJ
language	EN
topic	Science Q
spellingShingle	Science Q Mehmet S. Ozdas Aagam S. Shah Paul M. Johnson Nisheet Patel Markus Marks Tansel Baran Yasar Urs Stalder Laurent Bigler Wolfger von der Behrens Shashank R. Sirsi Mehmet Fatih Yanik Non-invasive molecularly-specific millimeter-resolution manipulation of brain circuits by ultrasound-mediated aggregation and uncaging of drug carriers
description	Non-invasive manipulation of brain circuits with molecular and spatial specificity could revolutionize the treatment of brain disorders. Here, the authors remotely concentrate and deliver drugs to focal brain regions without compromising the blood-brain barrier using novel ultrasound sequences and drug carriers.
format	article
author	Mehmet S. Ozdas Aagam S. Shah Paul M. Johnson Nisheet Patel Markus Marks Tansel Baran Yasar Urs Stalder Laurent Bigler Wolfger von der Behrens Shashank R. Sirsi Mehmet Fatih Yanik
author_facet	Mehmet S. Ozdas Aagam S. Shah Paul M. Johnson Nisheet Patel Markus Marks Tansel Baran Yasar Urs Stalder Laurent Bigler Wolfger von der Behrens Shashank R. Sirsi Mehmet Fatih Yanik
author_sort	Mehmet S. Ozdas
title	Non-invasive molecularly-specific millimeter-resolution manipulation of brain circuits by ultrasound-mediated aggregation and uncaging of drug carriers
title_short	Non-invasive molecularly-specific millimeter-resolution manipulation of brain circuits by ultrasound-mediated aggregation and uncaging of drug carriers
title_full	Non-invasive molecularly-specific millimeter-resolution manipulation of brain circuits by ultrasound-mediated aggregation and uncaging of drug carriers
title_fullStr	Non-invasive molecularly-specific millimeter-resolution manipulation of brain circuits by ultrasound-mediated aggregation and uncaging of drug carriers
title_full_unstemmed	Non-invasive molecularly-specific millimeter-resolution manipulation of brain circuits by ultrasound-mediated aggregation and uncaging of drug carriers
title_sort	non-invasive molecularly-specific millimeter-resolution manipulation of brain circuits by ultrasound-mediated aggregation and uncaging of drug carriers
publisher	Nature Portfolio
publishDate	2020
url	https://doaj.org/article/6a492392efd7456ea115ebf1a7ce1edc
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Non-invasive molecularly-specific millimeter-resolution manipulation of brain circuits by ultrasound-mediated aggregation and uncaging of drug carriers

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