One month use of Systane&reg; improves ocular surface parameters in subjects with moderate symptoms of ocular dryness

Piera Versura, Vincenzo Profazio, Emilio C CamposDepartment of Surgery and Anesthesiology, Section of Ophthalmology, Alma Mater Studiorum University at Bologna, Bologna, ItalyThe data in this paper were first presented at the 9th International Ocular Inflammation Society (IOIS) Annual Meeting, Septe...

Descripción completa

Guardado en:

Detalles Bibliográficos
Autores principales:	Piera Versura, Vincenzo Profazio, Emilio C Campos
Formato:	article
Lenguaje:	EN
Publicado:	Dove Medical Press 2008
Materias:	Ophthalmology RE1-994
Acceso en línea:	https://doaj.org/article/6a4c6270408347289d2c2b1d950da4f4
Etiquetas:	Agregar Etiqueta Sin Etiquetas, Sea el primero en etiquetar este registro!

id	oai:doaj.org-article:6a4c6270408347289d2c2b1d950da4f4
record_format	dspace
spelling	oai:doaj.org-article:6a4c6270408347289d2c2b1d950da4f42021-12-02T07:51:30ZOne month use of Systane&reg; improves ocular surface parameters in subjects with moderate symptoms of ocular dryness1177-54671177-5483https://doaj.org/article/6a4c6270408347289d2c2b1d950da4f42008-10-01T00:00:00Zhttp://www.dovepress.com/one-month-use-of-systanesupregsup-improves-ocular-surface-parameters-i-a2380https://doaj.org/toc/1177-5467https://doaj.org/toc/1177-5483Piera Versura, Vincenzo Profazio, Emilio C CamposDepartment of Surgery and Anesthesiology, Section of Ophthalmology, Alma Mater Studiorum University at Bologna, Bologna, ItalyThe data in this paper were first presented at the 9th International Ocular Inflammation Society (IOIS) Annual Meeting, September 17&ndash;20, 2007, Paris, France, and the European Association for Vision and Eye Research (EVER) Congress, October 3&ndash;6, 2007, Portoroz, SloveniaObjective: To evaluate the efficacy of Systane&reg; Lubricating Eye Drops in improving the symptoms of moderate ocular dryness.Methods: Fifty subjects with moderate symptoms of ocular dryness were enrolled in this open label study. The mean age of subjects was 57.6 &plusmn; 15.4 years. To be eligible, subjects&rsquo; tear film break-up time (TFBUT) had to be &lt;10 seconds, and subjects had to have at least one ocular discomfort symptom in addition to dryness. Saline was used for a wash-out period of 3&ndash;5 days. Subjects were re-examined, and those continuing to meet the inclusion criteria were dispensed Systane&reg; and re-examined again after 28 days. At each visit, slitlamp examination was conducted, and ocular discomfort symptoms and TFBUT were evaluated. Subjects rated their overall satisfaction at baseline and on the last visit.Results: No significant changes in TFBUT or ocular discomfort symptoms were observed after saline use, compared with screening visit. After 28 days of Systane&reg; use there was statistically significant improvement of TFBUT (p = 0.0001) compared with baseline. Subjects experienced significant symptomatic relief for all 6 ocular discomfort symptoms at the endpoint visit.Conclusion: Systane&reg; effectively relieved the symptoms associated with moderate ocular dryness, with measurable improvement in objective TFBUT, subjective symptoms, and overall satisfaction.Keywords: Systane, lubricant eye drops, TFBUT, ocular dryness, ocular symptoms Piera VersuraVincenzo ProfazioEmilio C CamposDove Medical PressarticleOphthalmologyRE1-994ENClinical Ophthalmology, Vol 2008, Iss Issue 3, Pp 629-635 (2008)
institution	DOAJ
collection	DOAJ
language	EN
topic	Ophthalmology RE1-994
spellingShingle	Ophthalmology RE1-994 Piera Versura Vincenzo Profazio Emilio C Campos One month use of Systane&reg; improves ocular surface parameters in subjects with moderate symptoms of ocular dryness
description	Piera Versura, Vincenzo Profazio, Emilio C CamposDepartment of Surgery and Anesthesiology, Section of Ophthalmology, Alma Mater Studiorum University at Bologna, Bologna, ItalyThe data in this paper were first presented at the 9th International Ocular Inflammation Society (IOIS) Annual Meeting, September 17&ndash;20, 2007, Paris, France, and the European Association for Vision and Eye Research (EVER) Congress, October 3&ndash;6, 2007, Portoroz, SloveniaObjective: To evaluate the efficacy of Systane&reg; Lubricating Eye Drops in improving the symptoms of moderate ocular dryness.Methods: Fifty subjects with moderate symptoms of ocular dryness were enrolled in this open label study. The mean age of subjects was 57.6 &plusmn; 15.4 years. To be eligible, subjects&rsquo; tear film break-up time (TFBUT) had to be &lt;10 seconds, and subjects had to have at least one ocular discomfort symptom in addition to dryness. Saline was used for a wash-out period of 3&ndash;5 days. Subjects were re-examined, and those continuing to meet the inclusion criteria were dispensed Systane&reg; and re-examined again after 28 days. At each visit, slitlamp examination was conducted, and ocular discomfort symptoms and TFBUT were evaluated. Subjects rated their overall satisfaction at baseline and on the last visit.Results: No significant changes in TFBUT or ocular discomfort symptoms were observed after saline use, compared with screening visit. After 28 days of Systane&reg; use there was statistically significant improvement of TFBUT (p = 0.0001) compared with baseline. Subjects experienced significant symptomatic relief for all 6 ocular discomfort symptoms at the endpoint visit.Conclusion: Systane&reg; effectively relieved the symptoms associated with moderate ocular dryness, with measurable improvement in objective TFBUT, subjective symptoms, and overall satisfaction.Keywords: Systane, lubricant eye drops, TFBUT, ocular dryness, ocular symptoms
format	article
author	Piera Versura Vincenzo Profazio Emilio C Campos
author_facet	Piera Versura Vincenzo Profazio Emilio C Campos
author_sort	Piera Versura
title	One month use of Systane&reg; improves ocular surface parameters in subjects with moderate symptoms of ocular dryness
title_short	One month use of Systane&reg; improves ocular surface parameters in subjects with moderate symptoms of ocular dryness
title_full	One month use of Systane&reg; improves ocular surface parameters in subjects with moderate symptoms of ocular dryness
title_fullStr	One month use of Systane&reg; improves ocular surface parameters in subjects with moderate symptoms of ocular dryness
title_full_unstemmed	One month use of Systane&reg; improves ocular surface parameters in subjects with moderate symptoms of ocular dryness
title_sort	one month use of systane&reg; improves ocular surface parameters in subjects with moderate symptoms of ocular dryness
publisher	Dove Medical Press
publishDate	2008
url	https://doaj.org/article/6a4c6270408347289d2c2b1d950da4f4
work_keys_str_mv	AT pieraversura onemonthuseofsystaneampregimprovesocularsurfaceparametersinsubjectswithmoderatesymptomsofoculardryness AT vincenzoprofazio onemonthuseofsystaneampregimprovesocularsurfaceparametersinsubjectswithmoderatesymptomsofoculardryness AT emilioccampos onemonthuseofsystaneampregimprovesocularsurfaceparametersinsubjectswithmoderatesymptomsofoculardryness
_version_	1718399160902746112

One month use of Systane&amp;reg; improves ocular surface parameters in subjects with moderate symptoms of ocular dryness

Ejemplares similares

One month use of Systane® improves ocular surface parameters in subjects with moderate symptoms of ocular dryness