AKAP95 regulates splicing through scaffolding RNAs and RNA processing factors

The chromatin-associated protein AKAP95 is known for its chromatin-related functions including enhancing transcription. Here the authors show that AKAP95 interacts with the splicing regulatory factors as well as RNAs to regulate the inclusion of exons and pre-mRNA splicing.

Guardado en:
Detalles Bibliográficos
Autores principales: Jing Hu, Alireza Khodadadi-Jamayran, Miaowei Mao, Kushani Shah, Zhenhua Yang, Md Talat Nasim, Zefeng Wang, Hao Jiang
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2016
Materias:
Q
Acceso en línea:https://doaj.org/article/6a5530b190df4e898f5958aba3f4b5b3
Etiquetas: Agregar Etiqueta
Sin Etiquetas, Sea el primero en etiquetar este registro!
id oai:doaj.org-article:6a5530b190df4e898f5958aba3f4b5b3
record_format dspace
spelling oai:doaj.org-article:6a5530b190df4e898f5958aba3f4b5b32021-12-02T17:31:34ZAKAP95 regulates splicing through scaffolding RNAs and RNA processing factors10.1038/ncomms133472041-1723https://doaj.org/article/6a5530b190df4e898f5958aba3f4b5b32016-11-01T00:00:00Zhttps://doi.org/10.1038/ncomms13347https://doaj.org/toc/2041-1723The chromatin-associated protein AKAP95 is known for its chromatin-related functions including enhancing transcription. Here the authors show that AKAP95 interacts with the splicing regulatory factors as well as RNAs to regulate the inclusion of exons and pre-mRNA splicing.Jing HuAlireza Khodadadi-JamayranMiaowei MaoKushani ShahZhenhua YangMd Talat NasimZefeng WangHao JiangNature PortfolioarticleScienceQENNature Communications, Vol 7, Iss 1, Pp 1-12 (2016)
institution DOAJ
collection DOAJ
language EN
topic Science
Q
spellingShingle Science
Q
Jing Hu
Alireza Khodadadi-Jamayran
Miaowei Mao
Kushani Shah
Zhenhua Yang
Md Talat Nasim
Zefeng Wang
Hao Jiang
AKAP95 regulates splicing through scaffolding RNAs and RNA processing factors
description The chromatin-associated protein AKAP95 is known for its chromatin-related functions including enhancing transcription. Here the authors show that AKAP95 interacts with the splicing regulatory factors as well as RNAs to regulate the inclusion of exons and pre-mRNA splicing.
format article
author Jing Hu
Alireza Khodadadi-Jamayran
Miaowei Mao
Kushani Shah
Zhenhua Yang
Md Talat Nasim
Zefeng Wang
Hao Jiang
author_facet Jing Hu
Alireza Khodadadi-Jamayran
Miaowei Mao
Kushani Shah
Zhenhua Yang
Md Talat Nasim
Zefeng Wang
Hao Jiang
author_sort Jing Hu
title AKAP95 regulates splicing through scaffolding RNAs and RNA processing factors
title_short AKAP95 regulates splicing through scaffolding RNAs and RNA processing factors
title_full AKAP95 regulates splicing through scaffolding RNAs and RNA processing factors
title_fullStr AKAP95 regulates splicing through scaffolding RNAs and RNA processing factors
title_full_unstemmed AKAP95 regulates splicing through scaffolding RNAs and RNA processing factors
title_sort akap95 regulates splicing through scaffolding rnas and rna processing factors
publisher Nature Portfolio
publishDate 2016
url https://doaj.org/article/6a5530b190df4e898f5958aba3f4b5b3
work_keys_str_mv AT jinghu akap95regulatessplicingthroughscaffoldingrnasandrnaprocessingfactors
AT alirezakhodadadijamayran akap95regulatessplicingthroughscaffoldingrnasandrnaprocessingfactors
AT miaoweimao akap95regulatessplicingthroughscaffoldingrnasandrnaprocessingfactors
AT kushanishah akap95regulatessplicingthroughscaffoldingrnasandrnaprocessingfactors
AT zhenhuayang akap95regulatessplicingthroughscaffoldingrnasandrnaprocessingfactors
AT mdtalatnasim akap95regulatessplicingthroughscaffoldingrnasandrnaprocessingfactors
AT zefengwang akap95regulatessplicingthroughscaffoldingrnasandrnaprocessingfactors
AT haojiang akap95regulatessplicingthroughscaffoldingrnasandrnaprocessingfactors
_version_ 1718380557674479616