AKAP95 regulates splicing through scaffolding RNAs and RNA processing factors
The chromatin-associated protein AKAP95 is known for its chromatin-related functions including enhancing transcription. Here the authors show that AKAP95 interacts with the splicing regulatory factors as well as RNAs to regulate the inclusion of exons and pre-mRNA splicing.
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Nature Portfolio
2016
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oai:doaj.org-article:6a5530b190df4e898f5958aba3f4b5b32021-12-02T17:31:34ZAKAP95 regulates splicing through scaffolding RNAs and RNA processing factors10.1038/ncomms133472041-1723https://doaj.org/article/6a5530b190df4e898f5958aba3f4b5b32016-11-01T00:00:00Zhttps://doi.org/10.1038/ncomms13347https://doaj.org/toc/2041-1723The chromatin-associated protein AKAP95 is known for its chromatin-related functions including enhancing transcription. Here the authors show that AKAP95 interacts with the splicing regulatory factors as well as RNAs to regulate the inclusion of exons and pre-mRNA splicing.Jing HuAlireza Khodadadi-JamayranMiaowei MaoKushani ShahZhenhua YangMd Talat NasimZefeng WangHao JiangNature PortfolioarticleScienceQENNature Communications, Vol 7, Iss 1, Pp 1-12 (2016) |
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Science Q Jing Hu Alireza Khodadadi-Jamayran Miaowei Mao Kushani Shah Zhenhua Yang Md Talat Nasim Zefeng Wang Hao Jiang AKAP95 regulates splicing through scaffolding RNAs and RNA processing factors |
description |
The chromatin-associated protein AKAP95 is known for its chromatin-related functions including enhancing transcription. Here the authors show that AKAP95 interacts with the splicing regulatory factors as well as RNAs to regulate the inclusion of exons and pre-mRNA splicing. |
format |
article |
author |
Jing Hu Alireza Khodadadi-Jamayran Miaowei Mao Kushani Shah Zhenhua Yang Md Talat Nasim Zefeng Wang Hao Jiang |
author_facet |
Jing Hu Alireza Khodadadi-Jamayran Miaowei Mao Kushani Shah Zhenhua Yang Md Talat Nasim Zefeng Wang Hao Jiang |
author_sort |
Jing Hu |
title |
AKAP95 regulates splicing through scaffolding RNAs and RNA processing factors |
title_short |
AKAP95 regulates splicing through scaffolding RNAs and RNA processing factors |
title_full |
AKAP95 regulates splicing through scaffolding RNAs and RNA processing factors |
title_fullStr |
AKAP95 regulates splicing through scaffolding RNAs and RNA processing factors |
title_full_unstemmed |
AKAP95 regulates splicing through scaffolding RNAs and RNA processing factors |
title_sort |
akap95 regulates splicing through scaffolding rnas and rna processing factors |
publisher |
Nature Portfolio |
publishDate |
2016 |
url |
https://doaj.org/article/6a5530b190df4e898f5958aba3f4b5b3 |
work_keys_str_mv |
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_version_ |
1718380557674479616 |