HIF1α regulates glioma chemosensitivity through the transformation between differentiation and dedifferentiation in various oxygen levels

Abstract Chemotherapy plays a significant role in glioma treatment; however, it has limited effectiveness in extending the life expectancies of glioma patients. Traditional studies have attributed this lack of efficacy to glioma stem cells (GSCs) and their high resistance to chemotherapy, and hypoxi...

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Autores principales: Pan Wang, Wenwu Wan, Shuanglong Xiong, Junwei Wang, Dewei Zou, Chuan Lan, Shuangjiang Yu, Bin Liao, Hua Feng, Nan Wu
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2017
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Acceso en línea:https://doaj.org/article/6a5b57193964410488125334d895996d
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