Structural basis of ligand binding modes at the human formyl peptide receptor 2

Structural basis of ligand binding modes at the human formyl peptide receptor 2

Formyl peptide receptors (FPRs) are GPCRs that play important roles in transducing chemotactic signals in phagocytes and mediating host-defense and inflammatory responses. Here the authors present the 2.8 Å crystal structure of human FPR2 in complex with the peptide agonist WKYMVm and in combination...

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Autores principales: Tong Chen, Muya Xiong, Xin Zong, Yunjun Ge, Hui Zhang, Mu Wang, Gye Won Han, Cuiying Yi, Limin Ma, Richard D. Ye, Yechun Xu, Qiang Zhao, Beili Wu
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2020
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Science
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Acceso en línea:https://doaj.org/article/6a6c3a3f8432461e92e7060e4f1bd1bd
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