The choice of the filtering method in microarrays affects the inference regarding dosage compensation of the active X-chromosome.
<h4>Background</h4>The hypothesis of dosage compensation of genes of the X chromosome, supported by previous microarray studies, was recently challenged by RNA-sequencing data. It was suggested that microarray studies were biased toward an over-estimation of X-linked expression levels as...
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Autores principales: | Raphaële Castagné, Maxime Rotival, Tanja Zeller, Philipp S Wild, Vinh Truong, David-Alexandre Trégouët, Thomas Munzel, Andreas Ziegler, François Cambien, Stefan Blankenberg, Laurence Tiret |
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Formato: | article |
Lenguaje: | EN |
Publicado: |
Public Library of Science (PLoS)
2011
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Materias: | |
Acceso en línea: | https://doaj.org/article/6a762a91bfd44c10886c9c5730c7ffe8 |
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