Enhancer and super-enhancer dynamics in repair after ischemic acute kidney injury

Acute kidney injury is a major health problem amongst hospitalized patients. Here the authors provide a comprehensive characterization of enhancer and super-enhancer elements, and the transcription factor motifs associated with these elements in response to kidney injury in vivo; providing insight i...

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Autores principales:	Julia Wilflingseder, Michaela Willi, Hye Kyung Lee, Hannes Olauson, Jakub Jankowski, Takaharu Ichimura, Reinhold Erben, M. Todd Valerius, Lothar Hennighausen, Joseph V. Bonventre
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2020
Materias:	Science Q
Acceso en línea:	https://doaj.org/article/6a7aaa51036f4e01a746e663fb07ffcc
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spelling	oai:doaj.org-article:6a7aaa51036f4e01a746e663fb07ffcc2021-12-02T16:24:53ZEnhancer and super-enhancer dynamics in repair after ischemic acute kidney injury10.1038/s41467-020-17205-52041-1723https://doaj.org/article/6a7aaa51036f4e01a746e663fb07ffcc2020-07-01T00:00:00Zhttps://doi.org/10.1038/s41467-020-17205-5https://doaj.org/toc/2041-1723Acute kidney injury is a major health problem amongst hospitalized patients. Here the authors provide a comprehensive characterization of enhancer and super-enhancer elements, and the transcription factor motifs associated with these elements in response to kidney injury in vivo; providing insight into the regulation of kidney repair.Julia WilflingsederMichaela WilliHye Kyung LeeHannes OlausonJakub JankowskiTakaharu IchimuraReinhold ErbenM. Todd ValeriusLothar HennighausenJoseph V. BonventreNature PortfolioarticleScienceQENNature Communications, Vol 11, Iss 1, Pp 1-14 (2020)
institution	DOAJ
collection	DOAJ
language	EN
topic	Science Q
spellingShingle	Science Q Julia Wilflingseder Michaela Willi Hye Kyung Lee Hannes Olauson Jakub Jankowski Takaharu Ichimura Reinhold Erben M. Todd Valerius Lothar Hennighausen Joseph V. Bonventre Enhancer and super-enhancer dynamics in repair after ischemic acute kidney injury
description	Acute kidney injury is a major health problem amongst hospitalized patients. Here the authors provide a comprehensive characterization of enhancer and super-enhancer elements, and the transcription factor motifs associated with these elements in response to kidney injury in vivo; providing insight into the regulation of kidney repair.
format	article
author	Julia Wilflingseder Michaela Willi Hye Kyung Lee Hannes Olauson Jakub Jankowski Takaharu Ichimura Reinhold Erben M. Todd Valerius Lothar Hennighausen Joseph V. Bonventre
author_facet	Julia Wilflingseder Michaela Willi Hye Kyung Lee Hannes Olauson Jakub Jankowski Takaharu Ichimura Reinhold Erben M. Todd Valerius Lothar Hennighausen Joseph V. Bonventre
author_sort	Julia Wilflingseder
title	Enhancer and super-enhancer dynamics in repair after ischemic acute kidney injury
title_short	Enhancer and super-enhancer dynamics in repair after ischemic acute kidney injury
title_full	Enhancer and super-enhancer dynamics in repair after ischemic acute kidney injury
title_fullStr	Enhancer and super-enhancer dynamics in repair after ischemic acute kidney injury
title_full_unstemmed	Enhancer and super-enhancer dynamics in repair after ischemic acute kidney injury
title_sort	enhancer and super-enhancer dynamics in repair after ischemic acute kidney injury
publisher	Nature Portfolio
publishDate	2020
url	https://doaj.org/article/6a7aaa51036f4e01a746e663fb07ffcc
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Enhancer and super-enhancer dynamics in repair after ischemic acute kidney injury

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