STUDY OF EPIDEMIOLOGICAL AND CLINICAL PROFILE OF CHILDHOOD GUILLAIN-BARRE SYNDROME AT THE CHILDREN’S HOSPITAL, LAHORE

Objective: To ascertain the demographic profile, diversity of clinical aspects of Guillain-Barre Syndrome (GBS) along with its prognosis. Study Design: Cross sectional study. Place and Duration of Study: Department of Pediatric Neurology, The Children’s Hospital Lahore, from Jul 2015 to Dec 20...

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Autores principales:	Faisal Zafar, Ahmad Omair Virk, Tipu Sultan, Zia Ur Rehman, Aadarsh Naz
Formato:	article
Lenguaje:	EN
Publicado:	Army Medical College Rawalpindi 2019
Materias:	antecedent illness guillain-barre syndrome polyradiculoneuropathy Medicine R Medicine (General) R5-920
Acceso en línea:	https://doaj.org/article/6a7c53bb26494379b26afb45431c5925
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spelling	oai:doaj.org-article:6a7c53bb26494379b26afb45431c59252021-11-12T03:46:18ZSTUDY OF EPIDEMIOLOGICAL AND CLINICAL PROFILE OF CHILDHOOD GUILLAIN-BARRE SYNDROME AT THE CHILDREN’S HOSPITAL, LAHORE0030-96482411-8842https://doaj.org/article/6a7c53bb26494379b26afb45431c59252019-06-01T00:00:00Zhttps://www.pafmj.org/index.php/PAFMJ/article/view/3040/2274https://doaj.org/toc/0030-9648https://doaj.org/toc/2411-8842Objective: To ascertain the demographic profile, diversity of clinical aspects of Guillain-Barre Syndrome (GBS) along with its prognosis. Study Design: Cross sectional study. Place and Duration of Study: Department of Pediatric Neurology, The Children’s Hospital Lahore, from Jul 2015 to Dec 2016. Material and Methods: One hundred and twenty five patients of both genders from the age of 1 to 15 years, fulfilling the inclusion criteria were included in the study. The clinical data were entered into proforma. Results: Out of the total, 77 (61.6%) were males and 48 (38.4%) were females. History of preceding illness was recorded in 57.6% of the patients and Upper Respiratory Tract Infection (URTI) 31.2% was the most common. 54.4% of the patients had cranial nerve paralysis. Upon electro diagnostic studies including electromyography (EMG) and nerve conduction studies (NCS) and clinical examination, there were 49 patients with acute inflammatory demyelinating polyradiculoneuropathy variant (AIDP), 67 had acute motor axonal neuropathy variant (AMAN), 6 patients having mixed and 3 patients with Miller Fischer syndrome (MFS). Treatment with intravenous immunoglobulins (IVIG) was given keeping in mind the indication. At 6 months follow up visit 89.6% of the patients had good outcome while 10.4% patients had poor outcome. Conclusion: The results of our study show that GBS is a disease with diverse clinical presentation. With the help of diagnostic facilities like EMG/NCS, well-equipped treatment and IVIG clinical outcome is good.Faisal ZafarAhmad Omair VirkTipu SultanZia Ur RehmanAadarsh NazArmy Medical College Rawalpindiarticleantecedent illnessguillain-barre syndromepolyradiculoneuropathyMedicineRMedicine (General)R5-920ENPakistan Armed Forces Medical Journal, Vol 69, Iss 3, Pp 611-616 (2019)
institution	DOAJ
collection	DOAJ
language	EN
topic	antecedent illness guillain-barre syndrome polyradiculoneuropathy Medicine R Medicine (General) R5-920
spellingShingle	antecedent illness guillain-barre syndrome polyradiculoneuropathy Medicine R Medicine (General) R5-920 Faisal Zafar Ahmad Omair Virk Tipu Sultan Zia Ur Rehman Aadarsh Naz STUDY OF EPIDEMIOLOGICAL AND CLINICAL PROFILE OF CHILDHOOD GUILLAIN-BARRE SYNDROME AT THE CHILDREN’S HOSPITAL, LAHORE
description	Objective: To ascertain the demographic profile, diversity of clinical aspects of Guillain-Barre Syndrome (GBS) along with its prognosis. Study Design: Cross sectional study. Place and Duration of Study: Department of Pediatric Neurology, The Children’s Hospital Lahore, from Jul 2015 to Dec 2016. Material and Methods: One hundred and twenty five patients of both genders from the age of 1 to 15 years, fulfilling the inclusion criteria were included in the study. The clinical data were entered into proforma. Results: Out of the total, 77 (61.6%) were males and 48 (38.4%) were females. History of preceding illness was recorded in 57.6% of the patients and Upper Respiratory Tract Infection (URTI) 31.2% was the most common. 54.4% of the patients had cranial nerve paralysis. Upon electro diagnostic studies including electromyography (EMG) and nerve conduction studies (NCS) and clinical examination, there were 49 patients with acute inflammatory demyelinating polyradiculoneuropathy variant (AIDP), 67 had acute motor axonal neuropathy variant (AMAN), 6 patients having mixed and 3 patients with Miller Fischer syndrome (MFS). Treatment with intravenous immunoglobulins (IVIG) was given keeping in mind the indication. At 6 months follow up visit 89.6% of the patients had good outcome while 10.4% patients had poor outcome. Conclusion: The results of our study show that GBS is a disease with diverse clinical presentation. With the help of diagnostic facilities like EMG/NCS, well-equipped treatment and IVIG clinical outcome is good.
format	article
author	Faisal Zafar Ahmad Omair Virk Tipu Sultan Zia Ur Rehman Aadarsh Naz
author_facet	Faisal Zafar Ahmad Omair Virk Tipu Sultan Zia Ur Rehman Aadarsh Naz
author_sort	Faisal Zafar
title	STUDY OF EPIDEMIOLOGICAL AND CLINICAL PROFILE OF CHILDHOOD GUILLAIN-BARRE SYNDROME AT THE CHILDREN’S HOSPITAL, LAHORE
title_short	STUDY OF EPIDEMIOLOGICAL AND CLINICAL PROFILE OF CHILDHOOD GUILLAIN-BARRE SYNDROME AT THE CHILDREN’S HOSPITAL, LAHORE
title_full	STUDY OF EPIDEMIOLOGICAL AND CLINICAL PROFILE OF CHILDHOOD GUILLAIN-BARRE SYNDROME AT THE CHILDREN’S HOSPITAL, LAHORE
title_fullStr	STUDY OF EPIDEMIOLOGICAL AND CLINICAL PROFILE OF CHILDHOOD GUILLAIN-BARRE SYNDROME AT THE CHILDREN’S HOSPITAL, LAHORE
title_full_unstemmed	STUDY OF EPIDEMIOLOGICAL AND CLINICAL PROFILE OF CHILDHOOD GUILLAIN-BARRE SYNDROME AT THE CHILDREN’S HOSPITAL, LAHORE
title_sort	study of epidemiological and clinical profile of childhood guillain-barre syndrome at the children’s hospital, lahore
publisher	Army Medical College Rawalpindi
publishDate	2019
url	https://doaj.org/article/6a7c53bb26494379b26afb45431c5925
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STUDY OF EPIDEMIOLOGICAL AND CLINICAL PROFILE OF CHILDHOOD GUILLAIN-BARRE SYNDROME AT THE CHILDREN’S HOSPITAL, LAHORE

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