Structural basis for promiscuous action of monoterpenes on TRP channels

Thi Hong Dung Nguyen et al. identify which regions within TRP channels TRPV1 and TRPV3 confer their sensitivity to monoterpenes that are major constituents of plant-derived essential oils. This study provides insights into how different TRP channels respond to chemical or heat stimuli.

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Bibliographic Details
Main Authors: Thi Hong Dung Nguyen, Satoru G. Itoh, Hisashi Okumura, Makoto Tominaga
Format: article
Language:EN
Published: Nature Portfolio 2021
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Online Access:https://doaj.org/article/6a7dd3a15c5c4a23879f93e96c0479e4
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Summary:Thi Hong Dung Nguyen et al. identify which regions within TRP channels TRPV1 and TRPV3 confer their sensitivity to monoterpenes that are major constituents of plant-derived essential oils. This study provides insights into how different TRP channels respond to chemical or heat stimuli.