Reversing the surface charge of MSC‐derived small extracellular vesicles by εPL‐PEG‐DSPE for enhanced osteoarthritis treatment
Abstract Mesenchymal stem cell‐derived small extracellular vesicles (MSC‐sEVs) possess a great therapeutical potential for osteoarthritis (OA) treatment. However, the steric and electrostatic hindrance of cartilage matrix leads to very limited distribution of MSC‐sEVs in cartilage and low bioavailab...
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Autores principales: | Kai Feng, Xuetao Xie, Ji Yuan, Liangzhi Gong, Zhaochen Zhu, Juntao Zhang, Haiyan Li, Yunlong Yang, Yang Wang |
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Formato: | article |
Lenguaje: | EN |
Publicado: |
Taylor & Francis Group
2021
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Materias: | |
Acceso en línea: | https://doaj.org/article/6a7f985ad6924ca88ea07e67d789fe61 |
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