Non-silent story on synonymous sites in voltage-gated ion channel genes.

Synonymous mutations are usually referred to as "silent", but increasing evidence shows that they are not neutral in a wide range of organisms. We looked into the relationship between synonymous codon usage bias and residue importance of voltage-gated ion channel proteins in mice, rats, an...

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Bibliographic Details
Main Authors: Tong Zhou, Eun A Ko, Wanjun Gu, Inja Lim, Hyoweon Bang, Jae-Hong Ko
Format: article
Language:EN
Published: Public Library of Science (PLoS) 2012
Subjects:
R
Q
Online Access:https://doaj.org/article/6a8352c3e2f84ea59e6e78921f9c1cfb
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