Genome-wide association study identifies susceptibility loci for B-cell childhood acute lymphoblastic leukemia
While GWAS have uncovered susceptibility loci for B-cell precursor acute lymphoblastic leukemia (BCP-ALL), much of the heritable risk remains undiscovered. Here, the authors perform a meta-analysis of two existing BCP-ALL GWAS together with an unpublished GWAS to identify risk loci at 8q24.21 and 2q...
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Nature Portfolio
2018
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oai:doaj.org-article:6a850276ab0d4ba1a6215db9280b774f2021-12-02T15:33:37ZGenome-wide association study identifies susceptibility loci for B-cell childhood acute lymphoblastic leukemia10.1038/s41467-018-03178-z2041-1723https://doaj.org/article/6a850276ab0d4ba1a6215db9280b774f2018-04-01T00:00:00Zhttps://doi.org/10.1038/s41467-018-03178-zhttps://doaj.org/toc/2041-1723While GWAS have uncovered susceptibility loci for B-cell precursor acute lymphoblastic leukemia (BCP-ALL), much of the heritable risk remains undiscovered. Here, the authors perform a meta-analysis of two existing BCP-ALL GWAS together with an unpublished GWAS to identify risk loci at 8q24.21 and 2q22.3.Jayaram VijayakrishnanJames StuddPeter BroderickBen KinnersleyAmy HolroydPhilip J. LawRajiv KumarJames M. AllanChristine J. HarrisonAnthony V. MoormanAjay VoraEve RomanSivaramakrishna RachakondaSally E. KinseyEamonn SheridanPamela D. ThompsonJulie A. IrvingRolf KoehlerPer HoffmannMarkus M. NöthenStefanie Heilmann-HeimbachKarl-Heinz JöckelDouglas F. EastonPaul D. P. PharaohAlison M. DunningJulian PetoFrederico CanzianAnthony SwerdlowRosalind A. EelesZSofia Kote-JaraiKenneth MuirNora PashayanThe PRACTICAL ConsortiumMel GreavesMartin ZimmermanClaus R. BartramMartin SchrappeMartin StanullaKari HemminkiRichard S. HoulstonNature PortfolioarticleScienceQENNature Communications, Vol 9, Iss 1, Pp 1-9 (2018) |
| institution |
DOAJ |
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DOAJ |
| language |
EN |
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Science Q |
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Science Q Jayaram Vijayakrishnan James Studd Peter Broderick Ben Kinnersley Amy Holroyd Philip J. Law Rajiv Kumar James M. Allan Christine J. Harrison Anthony V. Moorman Ajay Vora Eve Roman Sivaramakrishna Rachakonda Sally E. Kinsey Eamonn Sheridan Pamela D. Thompson Julie A. Irving Rolf Koehler Per Hoffmann Markus M. Nöthen Stefanie Heilmann-Heimbach Karl-Heinz Jöckel Douglas F. Easton Paul D. P. Pharaoh Alison M. Dunning Julian Peto Frederico Canzian Anthony Swerdlow Rosalind A. Eeles ZSofia Kote-Jarai Kenneth Muir Nora Pashayan The PRACTICAL Consortium Mel Greaves Martin Zimmerman Claus R. Bartram Martin Schrappe Martin Stanulla Kari Hemminki Richard S. Houlston Genome-wide association study identifies susceptibility loci for B-cell childhood acute lymphoblastic leukemia |
| description |
While GWAS have uncovered susceptibility loci for B-cell precursor acute lymphoblastic leukemia (BCP-ALL), much of the heritable risk remains undiscovered. Here, the authors perform a meta-analysis of two existing BCP-ALL GWAS together with an unpublished GWAS to identify risk loci at 8q24.21 and 2q22.3. |
| format |
article |
| author |
Jayaram Vijayakrishnan James Studd Peter Broderick Ben Kinnersley Amy Holroyd Philip J. Law Rajiv Kumar James M. Allan Christine J. Harrison Anthony V. Moorman Ajay Vora Eve Roman Sivaramakrishna Rachakonda Sally E. Kinsey Eamonn Sheridan Pamela D. Thompson Julie A. Irving Rolf Koehler Per Hoffmann Markus M. Nöthen Stefanie Heilmann-Heimbach Karl-Heinz Jöckel Douglas F. Easton Paul D. P. Pharaoh Alison M. Dunning Julian Peto Frederico Canzian Anthony Swerdlow Rosalind A. Eeles ZSofia Kote-Jarai Kenneth Muir Nora Pashayan The PRACTICAL Consortium Mel Greaves Martin Zimmerman Claus R. Bartram Martin Schrappe Martin Stanulla Kari Hemminki Richard S. Houlston |
| author_facet |
Jayaram Vijayakrishnan James Studd Peter Broderick Ben Kinnersley Amy Holroyd Philip J. Law Rajiv Kumar James M. Allan Christine J. Harrison Anthony V. Moorman Ajay Vora Eve Roman Sivaramakrishna Rachakonda Sally E. Kinsey Eamonn Sheridan Pamela D. Thompson Julie A. Irving Rolf Koehler Per Hoffmann Markus M. Nöthen Stefanie Heilmann-Heimbach Karl-Heinz Jöckel Douglas F. Easton Paul D. P. Pharaoh Alison M. Dunning Julian Peto Frederico Canzian Anthony Swerdlow Rosalind A. Eeles ZSofia Kote-Jarai Kenneth Muir Nora Pashayan The PRACTICAL Consortium Mel Greaves Martin Zimmerman Claus R. Bartram Martin Schrappe Martin Stanulla Kari Hemminki Richard S. Houlston |
| author_sort |
Jayaram Vijayakrishnan |
| title |
Genome-wide association study identifies susceptibility loci for B-cell childhood acute lymphoblastic leukemia |
| title_short |
Genome-wide association study identifies susceptibility loci for B-cell childhood acute lymphoblastic leukemia |
| title_full |
Genome-wide association study identifies susceptibility loci for B-cell childhood acute lymphoblastic leukemia |
| title_fullStr |
Genome-wide association study identifies susceptibility loci for B-cell childhood acute lymphoblastic leukemia |
| title_full_unstemmed |
Genome-wide association study identifies susceptibility loci for B-cell childhood acute lymphoblastic leukemia |
| title_sort |
genome-wide association study identifies susceptibility loci for b-cell childhood acute lymphoblastic leukemia |
| publisher |
Nature Portfolio |
| publishDate |
2018 |
| url |
https://doaj.org/article/6a850276ab0d4ba1a6215db9280b774f |
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