Metal Sulfide Semiconductor Nanomaterials and Polymer Microgels for Biomedical Applications

The development of nanomaterials with therapeutic and/or diagnostic properties has been an active area of research in biomedical sciences over the past decade. Nanomaterials have been identified as significant medical tools with potential therapeutic and diagnostic capabilities that are practically...

Descripción completa

Guardado en:
Detalles Bibliográficos
Autores principales: Athandwe M. Paca, Peter A. Ajibade
Formato: article
Lenguaje:EN
Publicado: MDPI AG 2021
Materias:
Acceso en línea:https://doaj.org/article/6a8826928a404491b11844c4e25bb82e
Etiquetas: Agregar Etiqueta
Sin Etiquetas, Sea el primero en etiquetar este registro!
id oai:doaj.org-article:6a8826928a404491b11844c4e25bb82e
record_format dspace
spelling oai:doaj.org-article:6a8826928a404491b11844c4e25bb82e2021-11-25T17:55:07ZMetal Sulfide Semiconductor Nanomaterials and Polymer Microgels for Biomedical Applications10.3390/ijms2222122941422-00671661-6596https://doaj.org/article/6a8826928a404491b11844c4e25bb82e2021-11-01T00:00:00Zhttps://www.mdpi.com/1422-0067/22/22/12294https://doaj.org/toc/1661-6596https://doaj.org/toc/1422-0067The development of nanomaterials with therapeutic and/or diagnostic properties has been an active area of research in biomedical sciences over the past decade. Nanomaterials have been identified as significant medical tools with potential therapeutic and diagnostic capabilities that are practically impossible to accomplish using larger molecules or bulk materials. Fabrication of nanomaterials is the most effective platform to engineer therapeutic agents and delivery systems for the treatment of cancer. This is mostly due to the high selectivity of nanomaterials for cancerous cells, which is attributable to the porous morphology of tumour cells which allows nanomaterials to accumulate more in tumour cells more than in normal cells. Nanomaterials can be used as potential drug delivery systems since they exist in similar scale as proteins. The unique properties of nanomaterials have drawn a lot of interest from researchers in search of new chemotherapeutic treatment for cancer. Metal sulfide nanomaterials have emerged as the most used frameworks in the past decade, but they tend to aggregate because of their high surface energy which triggers the thermodynamically favoured interaction. Stabilizing agents such as polymer and microgels have been utilized to inhibit the particles from any aggregations. In this review, we explore the development of metal sulfide polymer/microgel nanocomposites as therapeutic agents against cancerous cells.Athandwe M. PacaPeter A. AjibadeMDPI AGarticlesemiconductor nanomaterialsmetal sulfidetherapeutic agentsdrug deliverypolymer microgelsBiology (General)QH301-705.5ChemistryQD1-999ENInternational Journal of Molecular Sciences, Vol 22, Iss 12294, p 12294 (2021)
institution DOAJ
collection DOAJ
language EN
topic semiconductor nanomaterials
metal sulfide
therapeutic agents
drug delivery
polymer microgels
Biology (General)
QH301-705.5
Chemistry
QD1-999
spellingShingle semiconductor nanomaterials
metal sulfide
therapeutic agents
drug delivery
polymer microgels
Biology (General)
QH301-705.5
Chemistry
QD1-999
Athandwe M. Paca
Peter A. Ajibade
Metal Sulfide Semiconductor Nanomaterials and Polymer Microgels for Biomedical Applications
description The development of nanomaterials with therapeutic and/or diagnostic properties has been an active area of research in biomedical sciences over the past decade. Nanomaterials have been identified as significant medical tools with potential therapeutic and diagnostic capabilities that are practically impossible to accomplish using larger molecules or bulk materials. Fabrication of nanomaterials is the most effective platform to engineer therapeutic agents and delivery systems for the treatment of cancer. This is mostly due to the high selectivity of nanomaterials for cancerous cells, which is attributable to the porous morphology of tumour cells which allows nanomaterials to accumulate more in tumour cells more than in normal cells. Nanomaterials can be used as potential drug delivery systems since they exist in similar scale as proteins. The unique properties of nanomaterials have drawn a lot of interest from researchers in search of new chemotherapeutic treatment for cancer. Metal sulfide nanomaterials have emerged as the most used frameworks in the past decade, but they tend to aggregate because of their high surface energy which triggers the thermodynamically favoured interaction. Stabilizing agents such as polymer and microgels have been utilized to inhibit the particles from any aggregations. In this review, we explore the development of metal sulfide polymer/microgel nanocomposites as therapeutic agents against cancerous cells.
format article
author Athandwe M. Paca
Peter A. Ajibade
author_facet Athandwe M. Paca
Peter A. Ajibade
author_sort Athandwe M. Paca
title Metal Sulfide Semiconductor Nanomaterials and Polymer Microgels for Biomedical Applications
title_short Metal Sulfide Semiconductor Nanomaterials and Polymer Microgels for Biomedical Applications
title_full Metal Sulfide Semiconductor Nanomaterials and Polymer Microgels for Biomedical Applications
title_fullStr Metal Sulfide Semiconductor Nanomaterials and Polymer Microgels for Biomedical Applications
title_full_unstemmed Metal Sulfide Semiconductor Nanomaterials and Polymer Microgels for Biomedical Applications
title_sort metal sulfide semiconductor nanomaterials and polymer microgels for biomedical applications
publisher MDPI AG
publishDate 2021
url https://doaj.org/article/6a8826928a404491b11844c4e25bb82e
work_keys_str_mv AT athandwempaca metalsulfidesemiconductornanomaterialsandpolymermicrogelsforbiomedicalapplications
AT peteraajibade metalsulfidesemiconductornanomaterialsandpolymermicrogelsforbiomedicalapplications
_version_ 1718411866292617216