Prognostic factors and outcomes of unplanned extubation

Abstract This study investigated the prognostic factors and outcomes of unplanned extubation (UE) in patients in a medical center’s 6 intensive care units (ICUs) and calculated their mortality risk. We retrospectively reviewed the medical records of all adult patients in Chi Mei Medical Center who u...

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Autores principales:	Chien-Ming Chao, Mei-I. Sung, Kuo-Chen Cheng, Chih-Cheng Lai, Khee-Siang Chan, Ai-Chin Cheng, Shu-Chen Hsing, Chin-Ming Chen
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2017
Materias:	Medicine R Science Q
Acceso en línea:	https://doaj.org/article/6a88bae8957a4452a03e8417cf581b72
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spelling	oai:doaj.org-article:6a88bae8957a4452a03e8417cf581b722021-12-02T15:06:05ZPrognostic factors and outcomes of unplanned extubation10.1038/s41598-017-08867-12045-2322https://doaj.org/article/6a88bae8957a4452a03e8417cf581b722017-08-01T00:00:00Zhttps://doi.org/10.1038/s41598-017-08867-1https://doaj.org/toc/2045-2322Abstract This study investigated the prognostic factors and outcomes of unplanned extubation (UE) in patients in a medical center’s 6 intensive care units (ICUs) and calculated their mortality risk. We retrospectively reviewed the medical records of all adult patients in Chi Mei Medical Center who underwent UE between 2009 and 2015. During the study period, there were 305 episodes of UE in 295 ICU patients (men: 199 [67.5%]; mean age: 65.7 years; age range: 18–94 years). The mean Acute Physiology and Chronic Health Evaluation (APACHE) II score was 16.4, mean therapeutic intervention scoring system (TISS) score was 26.5, and mean Glasgow coma scale score was 10.4. One hundred thirty-six patients (46.1%) were re-intubated within 48 h. Forty-five died (mortality rate: 15.3%). Multivariate analyses showed 5 risk factors—respiratory rate, APACHE II score, uremia, liver cirrhosis, and weaning status—were independently associated with mortality. In conclusion, five risk factors including a high respiratory rate before UE, high APACHE II score, uremia, liver cirrhosis, and not in the process of being weaned—were associated with high mortality in patients who underwent UE.Chien-Ming ChaoMei-I. SungKuo-Chen ChengChih-Cheng LaiKhee-Siang ChanAi-Chin ChengShu-Chen HsingChin-Ming ChenNature PortfolioarticleMedicineRScienceQENScientific Reports, Vol 7, Iss 1, Pp 1-5 (2017)
institution	DOAJ
collection	DOAJ
language	EN
topic	Medicine R Science Q
spellingShingle	Medicine R Science Q Chien-Ming Chao Mei-I. Sung Kuo-Chen Cheng Chih-Cheng Lai Khee-Siang Chan Ai-Chin Cheng Shu-Chen Hsing Chin-Ming Chen Prognostic factors and outcomes of unplanned extubation
description	Abstract This study investigated the prognostic factors and outcomes of unplanned extubation (UE) in patients in a medical center’s 6 intensive care units (ICUs) and calculated their mortality risk. We retrospectively reviewed the medical records of all adult patients in Chi Mei Medical Center who underwent UE between 2009 and 2015. During the study period, there were 305 episodes of UE in 295 ICU patients (men: 199 [67.5%]; mean age: 65.7 years; age range: 18–94 years). The mean Acute Physiology and Chronic Health Evaluation (APACHE) II score was 16.4, mean therapeutic intervention scoring system (TISS) score was 26.5, and mean Glasgow coma scale score was 10.4. One hundred thirty-six patients (46.1%) were re-intubated within 48 h. Forty-five died (mortality rate: 15.3%). Multivariate analyses showed 5 risk factors—respiratory rate, APACHE II score, uremia, liver cirrhosis, and weaning status—were independently associated with mortality. In conclusion, five risk factors including a high respiratory rate before UE, high APACHE II score, uremia, liver cirrhosis, and not in the process of being weaned—were associated with high mortality in patients who underwent UE.
format	article
author	Chien-Ming Chao Mei-I. Sung Kuo-Chen Cheng Chih-Cheng Lai Khee-Siang Chan Ai-Chin Cheng Shu-Chen Hsing Chin-Ming Chen
author_facet	Chien-Ming Chao Mei-I. Sung Kuo-Chen Cheng Chih-Cheng Lai Khee-Siang Chan Ai-Chin Cheng Shu-Chen Hsing Chin-Ming Chen
author_sort	Chien-Ming Chao
title	Prognostic factors and outcomes of unplanned extubation
title_short	Prognostic factors and outcomes of unplanned extubation
title_full	Prognostic factors and outcomes of unplanned extubation
title_fullStr	Prognostic factors and outcomes of unplanned extubation
title_full_unstemmed	Prognostic factors and outcomes of unplanned extubation
title_sort	prognostic factors and outcomes of unplanned extubation
publisher	Nature Portfolio
publishDate	2017
url	https://doaj.org/article/6a88bae8957a4452a03e8417cf581b72
work_keys_str_mv	AT chienmingchao prognosticfactorsandoutcomesofunplannedextubation AT meiisung prognosticfactorsandoutcomesofunplannedextubation AT kuochencheng prognosticfactorsandoutcomesofunplannedextubation AT chihchenglai prognosticfactorsandoutcomesofunplannedextubation AT kheesiangchan prognosticfactorsandoutcomesofunplannedextubation AT aichincheng prognosticfactorsandoutcomesofunplannedextubation AT shuchenhsing prognosticfactorsandoutcomesofunplannedextubation AT chinmingchen prognosticfactorsandoutcomesofunplannedextubation
_version_	1718388587920097280

Prognostic factors and outcomes of unplanned extubation

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