Nephrotic syndrome after treatment of Crohn′s disease with mesalamine: Case report and literature review

Inflammatory bowel disease and its various treatments may affect the kidney in several ways. Recently, case reports have been published documenting the development of nephrotic syndrome after the treatment for inflammatory bowel disease with 5-aminosalicylic acid derivatives. We report a 50-year-old...

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Autores principales: Belal M Firwana, Rim Hasan, Walid Chalhoub, Mazen Ferwana, Jin-Yong Kang, Joshua Aron, Joseph Lieber
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Publicado: Thieme Medical and Scientific Publishers Pvt. Ltd. 2012
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Acceso en línea:https://doaj.org/article/6a8c55573a024d3695735d2d905dc4ed
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spelling oai:doaj.org-article:6a8c55573a024d3695735d2d905dc4ed2021-12-02T17:59:19ZNephrotic syndrome after treatment of Crohn′s disease with mesalamine: Case report and literature review2231-07702249-446410.4103/2231-0770.94804https://doaj.org/article/6a8c55573a024d3695735d2d905dc4ed2012-01-01T00:00:00Zhttp://www.thieme-connect.de/DOI/DOI?10.4103/2231-0770.94804https://doaj.org/toc/2231-0770https://doaj.org/toc/2249-4464Inflammatory bowel disease and its various treatments may affect the kidney in several ways. Recently, case reports have been published documenting the development of nephrotic syndrome after the treatment for inflammatory bowel disease with 5-aminosalicylic acid derivatives. We report a 50-year-old patient who was diagnosed with Crohn′s disease and was treated with mesalamine. The patient subsequently developed nephrotic syndrome and a renal biopsy showed minimal change disease. He was treated with losartan and rosuvastatin and showed improvement in his renal function and serum cholesterol level. This is the first reported case in Crohn′s disease although there have been six previous case reports of nephrotic syndrome following salicylic acid derivatives for ulcerative colitis.Belal M FirwanaRim HasanWalid ChalhoubMazen FerwanaJin-Yong KangJoshua AronJoseph LieberThieme Medical and Scientific Publishers Pvt. Ltd.articleaminosalicylic acidcrohn′s diseaseinflammatory bowel diseasemesalamineminimal change diseasenephrotic syndromeMedicineRENAvicenna Journal of Medicine, Vol 02, Iss 01, Pp 9-11 (2012)
institution DOAJ
collection DOAJ
language EN
topic aminosalicylic acid
crohn′s disease
inflammatory bowel disease
mesalamine
minimal change disease
nephrotic syndrome
Medicine
R
spellingShingle aminosalicylic acid
crohn′s disease
inflammatory bowel disease
mesalamine
minimal change disease
nephrotic syndrome
Medicine
R
Belal M Firwana
Rim Hasan
Walid Chalhoub
Mazen Ferwana
Jin-Yong Kang
Joshua Aron
Joseph Lieber
Nephrotic syndrome after treatment of Crohn′s disease with mesalamine: Case report and literature review
description Inflammatory bowel disease and its various treatments may affect the kidney in several ways. Recently, case reports have been published documenting the development of nephrotic syndrome after the treatment for inflammatory bowel disease with 5-aminosalicylic acid derivatives. We report a 50-year-old patient who was diagnosed with Crohn′s disease and was treated with mesalamine. The patient subsequently developed nephrotic syndrome and a renal biopsy showed minimal change disease. He was treated with losartan and rosuvastatin and showed improvement in his renal function and serum cholesterol level. This is the first reported case in Crohn′s disease although there have been six previous case reports of nephrotic syndrome following salicylic acid derivatives for ulcerative colitis.
format article
author Belal M Firwana
Rim Hasan
Walid Chalhoub
Mazen Ferwana
Jin-Yong Kang
Joshua Aron
Joseph Lieber
author_facet Belal M Firwana
Rim Hasan
Walid Chalhoub
Mazen Ferwana
Jin-Yong Kang
Joshua Aron
Joseph Lieber
author_sort Belal M Firwana
title Nephrotic syndrome after treatment of Crohn′s disease with mesalamine: Case report and literature review
title_short Nephrotic syndrome after treatment of Crohn′s disease with mesalamine: Case report and literature review
title_full Nephrotic syndrome after treatment of Crohn′s disease with mesalamine: Case report and literature review
title_fullStr Nephrotic syndrome after treatment of Crohn′s disease with mesalamine: Case report and literature review
title_full_unstemmed Nephrotic syndrome after treatment of Crohn′s disease with mesalamine: Case report and literature review
title_sort nephrotic syndrome after treatment of crohn′s disease with mesalamine: case report and literature review
publisher Thieme Medical and Scientific Publishers Pvt. Ltd.
publishDate 2012
url https://doaj.org/article/6a8c55573a024d3695735d2d905dc4ed
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AT walidchalhoub nephroticsyndromeaftertreatmentofcrohnsdiseasewithmesalaminecasereportandliteraturereview
AT mazenferwana nephroticsyndromeaftertreatmentofcrohnsdiseasewithmesalaminecasereportandliteraturereview
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